ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025
Sex-based differences in biomechanical function for chronic low back pain and how it relates to pain experience.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
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Who cites it
6 citing papers in PubMed.
- Patient-Reported Knee Function Versus Star Excursion Balance Performance as Correlates of Psychological Return-to-Sport Readiness After Anterior Cruciate Ligament Reconstruction.Bioengineering (Basel, Switzerland) · 2026Article
- Sex Differences in Experiencing and Reporting Low Back Pain Using Standardised Questionnaires: A Cross-Sectional Study.Musculoskeletal care · 2026Observational
- Comparing Movement Patterns and Physical Function Between Chronic Low Back Pain Patients With Nociplastic and Nociceptive Pain Categories.JOR spine · 2026Article
- Load-induced alterations in posterior parts of intervertebral discs in patients with load-induced pain during MRI; a detailed study using T2 maps.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- 3D motion capture data into a kinematic composite score for assessing musculoskeletal impairments.Journal of biomechanics · 2025Article
- Physician referrals of patients with neck and low back pain for physical therapy in outpatient clinics: a cross-sectional study.Israel journal of health policy research · 2025Article
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Authors and funding
14 authors.
Funding
Abstract
purposeThe relationship between pain experience and biomechanical impairment in chronic low back pain (LBP) is unclear. Among the broader pain literature, sex-based differences in pain experience have been established. However, it is unknown if sex-based differences in pain experience relates to compromised movement patterns for patients with chronic LBP. This study examined sex differences and whether there are sex-based associations between pain experience and biomechanical function in patients with chronic LBP.
methodsTo capture the biomechanical variability among LBP patients, we quantified full-body movement quality based on the extent that 3D postural trajectories deviated from matched controls during a sit-to-stand task (Kinematic Composite Score, K-Score). For both males and females, the K-Score was compared to pain measures, including patient-reported metrics and quantitative sensory testing (pressure pain threshold, PPT).
resultsThere were significant sex-based differences in pain experience and biomechanical function in patients with LBP. Specifically, males exhibited ~ 8% lower trunk K-Scores, indicating biomechanical function that deviated more from controls when compared to female participants (p < 0.001). However, females exhibited PPT values 29% and 41% lower than males at the control and pain sites, respectively (p < 0.0001). There was a weak but significant negative association between PPT and K-Scores for males (R
conclusionOverall, males with LBP exhibited worse movement quality, driven by trunk motion, but higher PPTs. Possible explanations include reduced interoceptive awareness or increased kinesiophobia in males, which may influence movement patterns. This research is an initial step in uncovering the complex relationship between patient-specific factors influencing LBP disability, laying the groundwork for further exploration, and paving the way for improving outcomes with patient-specific treatments.
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Registered trials
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