Evidence map›Paper›PMID 40111450›Full record

ArticleInternational orthopaedics2025

Reinforced lengthening Achilles tendon Z-plasty - ex vivo assessment of biomechanical augmentation with surgical-fiberlock technology.

Thomas Dreher, Andrea Moehl, Elias Bachmann, Arend Nieuwland, Jess G Snedeker

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Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microneedles: Selected Applications for Pediatrics.Children (Basel, Switzerland) · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas DreherDepartment of Pediatric Orthopedics, Balgrist University Hospital Zurich, University of Zurich, Zurich, Switzerland. thomas.dreher@kispi.uzh.ch.ORCID 0000-0002-4166-5207
Andrea MoehlZurimed Technologies AG, Zurich, Switzerland.ORCID 0009-0002-5657-4727
Elias BachmannZurimed Technologies AG, Zurich, Switzerland.ORCID 0000-0002-1422-3104
Arend NieuwlandDepartment of Pediatric Orthopedics, Balgrist University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-5676-6839
Jess G SnedekerZurimed Technologies AG, Zurich, Switzerland.ORCID 0000-0002-8115-0275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTendon lengthening is a common lower limb surgical procedure in paediatric orthopaedics and deformity correction. Healing of a lengthened tendon is typically supported by casting and unloading of the operated limb. Although tendon rupture or overcorrection may adversely affect surgical outcomes, few studies have examined surgical means of improving post-operative stability of the tendon. We aim to evaluate a novel method for augmenting Z-Plasty tendon lengthening as a first step to clinical translation.

methodsIn this experimental ex vivo study, we employed a bovine flexor tendon model (n = 18) to examine a novel mechanical augmentation method after tendon lengthening by Z-plasty. Conventional surgical suturing of the imposed Z-plasty (n = 6) and an experimental group (n = 6), in which additional augmentation was performed by interlocking fibres of a biomaterial scaffold to the underlying tendon using a novel micro-needling technique, were compared to native tendons (n = 6).

resultsThe needle interlocked scaffold successfully augmented the suture repair, showing more than doubled ultimate failure force compared to controls (482 ± 107 N vs. 206 ± 37 N, p < 0.01), and more than 1.5-fold repair stiffness (41 ± 7 N/mm vs. 26 ± 9 N/mm, p < 0.01).

conclusionWe conclude that the use of an interpenetrating biomaterial scaffold represents a promising new approach for improving biomechanical tendon properties, which may have an implication on the stability of tendon suture, lengthening and tendon transfer procedures as well as on post-operative management and earlier mobilization.

Indexed as

Achilles TendonSuture TechniquesTenotomyAnimalsBiomechanical PhenomenaCattleTendon InjuriesTissue Scaffolds

Identifiers

PMID40111450
PMCPMC12003439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.