Evidence map›Paper›PMID 40111008›Full record

ArticleEuropean journal of immunology2025

Epigenetic Regulation of CD8

Lixue Jin, Xin Zhang, Jingyi Wang, Yujia Wang, Ke Wang, Zhuolin Wang, Pingzhang Wang, Xiuyuan Sun, Jie Hao, Rong Jin and 2 more

Abstract read
In one paragraph

Article in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lixue JinDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Xin ZhangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China.
Jingyi WangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Yujia WangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Ke WangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Zhuolin WangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Pingzhang WangDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Xiuyuan SunDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Jie HaoDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Rong JinDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.
Dan LuDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Beijing, China.
Qing GeDepartment of Immunology, School of Basic Medical Sciences, NHC Key Laboratory of Medical Immunology, Beijing Key Laboratory of Tumor Systems Biology, Institute of Systems Biomedicine, Peking University Health Science Center, Peking University, Beijing, China.

Funding

Beijing Natural Science Foundation 7242087Guo Zhong Health Care of China General Technology Group 20230626National Key R&D Program of China 2023YFB3507002National Natural Science Foundation of China 32270935Non-Profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2018PT31039
6 · The paper itself

Abstract

Epigenetic modification plays a crucial role in establishing the transcriptional program that governs the differentiation of CD8

Indexed as

Apoptosis Regulatory ProteinsCD8-Positive T-LymphocytesCell DifferentiationEpigenesis, GeneticAnimalsHistone-Lysine N-MethyltransferaseLymphocyte ActivationMiceMice, Inbred C57BLMice, KnockoutNeoplasm ProteinsT-Box Domain ProteinsApoptosis Regulatory ProteinsHistone-Lysine N-MethyltransferaseNeoplasm ProteinsPdcd5 protein, mouseT-Box Domain ProteinsCD8+ T cellseffector T cell differentiationepigenetic modificationLCMV Clone 13 virusPDCD5

Identifiers

PMID40111008
PMCPMC11924876

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.