Evidence map›Paper›PMID 40110992›Full record

ArticleCancer communications (London, England)2025

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis.

Lea Järke, Saskia Weber-Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer communications (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Lea JärkeInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Saskia Weber-StiehlInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Kensuke ShimaInstitute of Medical Microbiology, University of Lübeck, Lübeck, Germany.
Karlis Arturs MoorsInstitute of Experimental Medicine, Kiel University, Kiel, Germany.
Jerome GenthInstitute of Experimental Medicine, Kiel University, Kiel, Germany.
Fenja Amrei SchuranInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Lena BestInstitute of Experimental Medicine, Kiel University, Kiel, Germany.
Markus TschurtschenthalerTranslational Cancer Research and Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0002-0060-4790
Burkhardt FlemerInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Silke LüschenDepartment of Pathology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Christoph RöckenDepartment of Pathology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Andreas TholeyInstitute of Experimental Medicine, Kiel University, Kiel, Germany.
Christoph KaletaInstitute of Experimental Medicine, Kiel University, Kiel, Germany.
Jan RuppInstitute of Medical Microbiology, University of Lübeck, Lübeck, Germany.
Philip RosenstielInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
Felix SommerInstitute of Clinical Molecular Biology, Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-6545-3487

Funding

Excellence Cluster EXS2167German Research Foundation SO1141/10-1Intramural grant of the medical faculty of Kiel University F384430Intramural grant of the medical faculty of Kiel University K126408Research Unit FOR5042
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40110992
PMCPMC12328089

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.