Evidence map›Paper›PMID 40110865›Full record

ArticleAnimal biotechnology2025

Enhanced susceptibility of porcine muscle-derived mesenchymal stem cells to Aujeszky's virus compared Vero cells.

Na-Yeon Gu, Gwang Sik Ryu, Gyu-Nam Park, Ju-Yeon Lee, Yun Sang Cho, Dong-Kun Yang, Hye Jeong Lee

Abstract read
In one paragraph

Article in Animal biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Na-Yeon GuViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Gwang Sik RyuViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Gyu-Nam ParkViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Ju-Yeon LeeViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Yun Sang ChoViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Dong-Kun YangViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.
Hye Jeong LeeViral Disease Division, Animal and Plant Quarantine Agency, Gyeongsangbuk-do, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) can self-renew and differentiate into several lineages and can be isolated from different tissues such as bone marrow, adipose tissue, umbilical cord blood, and muscle. Herein, we established MSCs derived from miniature pig muscle (MpMu-MSCs) and assessed their response to Aujeszky's virus. We characterized the MpMu-MSCs based on their cellular morphology, proliferation properties, cell surface marker expression, and mesodermal differentiation potential. MpMu-MSCs demonstrated a fibroblast-like spindle shape and formed a homogeneous monolayer. They showed a considerable increase in cell proliferation over 16 passages. The cells expressed surface markers CD29, CD44, CD90, and CD105 and demonstrated mesodermal lineage differentiation capabilities. MpMu-MSCs demonstrated faster cytopathic effects than the Vero cells when infected with Aujeszky's virus. The virus titer in MpMu-MSCs was initiated at 10

Indexed as

Herpesvirus 1, SuidMesenchymal Stem CellsMuscle, SkeletalAnimalsCell DifferentiationCell ProliferationCells, CulturedChlorocebus aethiopsSwineSwine, MiniatureVero CellsAdult stem cellAujeszky’s virusmesenchymal stem cellporcine

Identifiers

PMID40110865
PMCPMC12674294

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.