SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
Effectiveness of mandibular advancement devices in obstructive sleep apnea therapy for East Asian patients: a systematic review and meta-analysis.
Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Is Maxillomandibular Advancement Possible in Skeletal Class III Patients? A Scoping Review.Journal of clinical medicine · 2026Review
- Long-term upper airway changes following mandibular advancement with or without maxillary setback in skeletal class II patients: a 2-year retrospective study.BMC oral health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prior studies have shown that a mandibular advancement device (MAD) is an effective nonsurgical treatment for obstructive sleep apnea. Most studies were performed in primarily White populations. However, East Asians have restrictive craniofacial features, such as a reduced cranial base, maxilla, and retropalatal space, which may affect their response to treatment. The objective of this study was to systematically review the use of MAD in East Asian patients and determine the effectiveness of MAD in this population. The PubMed, Embase, Scopus, CINAHL, Web of Science, and Cochrane Library databases were searched up to January 15, 2024. Studies that investigated the effects of MAD on the apnea-hypopnea index, oxygen saturation, blood pressure, and Epworth Sleepiness Scale score specifically for East Asian patients were included. Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed for data extraction. Twelve studies with 382 patients were included. The pooled mean reduction in apnea-hypopnea index was 19.1 (95% confidence interval [CI] = -23.9; -14.3, CITATION: Yong CW, Quah B, Colpani JT, Lee FKF, Loh EE-M, Wong RCW. Effectiveness of mandibular advancement devices in obstructive sleep apnea therapy for East Asian patients: a systematic review and meta-analysis.
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Registered trials
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