ArticleAlpha psychiatry2025
Neurosyphilis Diagnosis and Treatment in Psychiatric Hospitals: A Retrospective Study.
Article in Alpha psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A distinct IgM immunoblot signature differentiates neurosyphilis from latent syphilis.Microbiology spectrum · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Neurosyphilis, caused by Methods: A retrospective study used data from the Chinese Case Report System (CCRS) spanning 2014-2018. Four municipal psychiatric hospitals in Guangdong were chosen based on syphilis rates and psychiatric patient volumes. Sociodemographic data, syphilis history, symptoms, diagnostic and treatment details, and laboratory results were reviewed. The Brief Psychiatric Rating Scale (BPRS) assessed psychopathology symptoms. Treatment efficacy was evaluated using BPRS scores before and after standard treatment. Diagnoses followed national guidelines, with statistical analyses performed using logistic regression and Results: Out of 69,436 psychosis patients screened, 1588 were diagnosed with syphilis, with 262 (16.5%) of these cases identified as neurosyphilis. Syphilis prevalence mildly declined from 2.8% (2014) to 2.0% (2016), while neurosyphilis cases increased marginally from 0.34% (2014) to 0.39% (2018). Confirmatory Cerebrospinal Fluid (CSF) tests were conducted in only 30.2% of neurosyphilis cases. Standard therapy was administered to 66.8% of patients, with significantly better outcomes in confirmed cases ( Conclusions: Diagnosing and treating neurosyphilis in Guangdong's psychiatric hospitals remains challenging. Accurate diagnosis and standardized treatment protocols are essential to effectively manage both syphilis and associated mental health complications caused by neurosyphilis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.