Development of Repetitive Mechanical Oscillation Needle-Free Injection through Electrically Induced Microbubbles.

Yibo Ma, Wenjing Huang, Naotomo Tottori, Yoko Yamanishi

Abstract read

In one paragraph

Article in Cyborg and bionic systems (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

A needle-free bubble injector enabling depth-controlled isotropic and anisotropic perforation using electrically induced bubbles and heat generated by electric discharge.Biomedical microdevices · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yibo MaBio-medical Fluid Engineering Laboratory, Mechanical Engineering, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0009-0002-2445-9812

Wenjing HuangKindai University Technical College, Mie, Japan.

Naotomo TottoriBio-medical Fluid Engineering Laboratory, Mechanical Engineering, Kyushu University, Fukuoka, Japan.

Yoko YamanishiBio-medical Fluid Engineering Laboratory, Mechanical Engineering, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0001-7193-9339

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously developed a novel needle-free reagent injection method based on electrically induced microbubbles. The system generates microbubbles and applies repetitive mechanical oscillation associated with microbubble dynamics to perforate tissue and introduce a reagent. In this paper, we propose improving the reagent injection depth by reflecting the shock wave through microbubble dynamics. Our results show that the developed shock wave reflection method improves the ability of the electrically induced microbubble injection system to introduce a reagent. The method extends the application potential of electrically induced microbubble needle-free injection.

Identifiers

PMID40110347

DOI10.34133/cbsystems.0225

PMCPMC11919823

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.