Evidence map›Paper›PMID 40110293›Full record

ReviewAnnals of medicine and surgery (2012)2025

Essential information about nanotechnology in cardiology.

Chukwuka Elendu, Dependable C Amaechi, Tochi C Elendu, Emmanuel C Amaechi, Ijeoma D Elendu, Janet C Omeludike, Eunice K Omeludike, Nwamaka C Onubogu, Emmanuel C Ogelle, Oluwatobi O M Meduoye and 6 more

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Recent Advances in Aptamer-Based Applications in Cardiology.International journal of molecular sciences · 2026
    Review
  3. Applications of Nanobiotechnology in Medicine.Life (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chukwuka ElenduFederal University Teaching Hospital, Owerri, Nigeria.
Dependable C AmaechiIgbinedion University, Okada, Nigeria.
Tochi C ElenduImo State University, Owerri, Nigeria.
Emmanuel C AmaechiMadonna University, Elele, Nigeria.
Ijeoma D ElenduImo State University, Owerri, Nigeria.
Janet C OmeludikeUniversity of Chester, Chester, United Kingdom.
Eunice K OmeludikeUniversity of Portharcourt, Choba, Nigeria.
Nwamaka C OnuboguAbia State University, Uturu, Nigeria.
Emmanuel C OgelleBlessed Specialist Hospital, Onitsha, Nigeria.
Oluwatobi O M MeduoyeGlasgow Caledonian University, Glasgow, United Kingdom.
Praise O OloyedeSt. Nicholas Hospital, Lagos, Nigeria.
Chiamaka P EzehUniversity of Portharcourt, Choba, Nigeria.
Ikpembhosa J EsangbedoUniversity College hospital, Ibadan, Nigeria.
Augustina C AdigweZaporizhzhia State Medical University, Zaporizhzhia, Ukraine.
Nnachi M AkumaUniversity of Portharcourt, Choba, Nigeria.
Silas U OkaforUniversity College hospital, Ibadan, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiology, as a medical specialty, addresses cardiovascular diseases (CVDs), a leading cause of global mortality. Nanomaterials offer transformative potential across key areas such as drug delivery, stem cell therapy, imaging, and gene delivery. Nanomaterials improve solubility, bioavailability, and targeted delivery in drug delivery, reducing systemic side effects. Examples include gas microbubbles, liposomal preparations, and paramagnetic nanoparticles, which show promise in treating atherosclerosis. Stem cell therapy benefits from nanotechnology through enhanced cell culture conditions and three-dimensional scaffolds that support cardiomyocyte growth and survival. Gold nanoparticles and poly(lactic-co-glycolic acid)-derived microparticles further improve stem cell viability. In imaging, nanomaterials enable advanced visualization techniques such as magnetic resonance imaging with direct labeling and optical tracking via dye-conjugated nanoparticles. In gene delivery, polymeric nanocarriers like polyethyleneimine, dendrimers, and graphene-based materials offer efficient, non-viral alternatives, with magnetic nanoparticles showing promise in targeted applications. Ongoing research highlights the potential of nanomaterials to revolutionize CVD management by improving therapeutic outcomes and enabling precision medicine. These advancements position nanotechnology as a cornerstone of modern cardiology.

Indexed as

cardiologynanomedicinenanoparticlesnanotechnologytherapeutics

Identifiers

PMID40110293
PMCPMC11918598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.