ReviewCureus2025
Raman Spectroscopy in the Diagnosis of Brain Gliomas: A Literature Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Raman spectroscopy as a diagnostic tool for glioma: protocol for a systematic review.Diagnostic and prognostic research · 2026Review
- Stimulated Raman Spectroscopy for Intraoperative Glioblastoma Diagnosis-A Complementary Tool to Frozen Section?Cancers · 2026Article
- Towards Optical Biopsy in Glioma Surgery.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Raman spectroscopy (RS) is increasingly applied in medical fields to distinguish neoplastic from normal tissues, with recent advancements enabling its use in neurosurgery. This review explores RS as a diagnostic and surgical aid for brain gliomas, detailing its various modalities and applications. Through a comprehensive search in databases including PubMed, Google Scholar, and eLibrary, over 300 references were screened, resulting in 74 articles that met inclusion criteria. Key findings reveal RS's potential in neuro-oncology for examining native biopsy specimens, frozen and paraffin-embedded tissues, and body fluids, as well as performing intraoperative assessments. RS offers promise for identifying gliomas, differentiating them from healthy brain tissue, and establishing precise tumor boundaries during resection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.