Evidence map›Paper›PMID 40109771›Full record

ArticleOpen life sciences2025

Application of metagenomic next-generation sequencing in the diagnosis of pathogens in patients with diabetes complicated by community-acquired pneumonia.

Hong-Bo Chen, Jie Liu, Yu Zhang, Hao Huang, Li-Na Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hong-Bo ChenDepartment Respiratory Medicine, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, No. 2 of South Gang He Road, Anning, Kunming, 650302, Yunnan, China.
Jie LiuDepartment Respiratory Medicine, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, No. 2 of South Gang He Road, Anning, Kunming, 650302, Yunnan, China.
Yu ZhangDepartment Respiratory Medicine, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, No. 2 of South Gang He Road, Anning, Kunming, 650302, Yunnan, China.
Hao HuangDepartment Medical Records Statistics Section, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, No. 2 of South Gang He Road, Anning, Kunming, 650302, Yunnan, China.
Li-Na WangDepartment Respiratory Medicine, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, No. 2 of South Gang He Road, Anning, Kunming, 650302, Yunnan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the clinical utility and optimal timing of metagenomic next-generation sequencing (mNGS) in diagnosing pathogens in patients with diabetes complicated by community-acquired pneumonia (CAP). The study included 50 hospitalized patients diagnosed with diabetes complicated by CAP who underwent conventional microbiological testing (CMT) and mNGS using bronchoalveolar lavage fluid. Among the 50 cases, 16% presented no respiratory symptoms. There were significant increases in inflammatory markers such as C-reactive protein, erythrocyte sedimentation rate, and interleukin-6, with patchy imaging changes being the most prevalent. The positive rates for pathogen detection by mNGS and CMTs were 78 and 21% (

Indexed as

bronchoalveolar lavage fluidcommunity-acquired pneumoniadiabetesmetagenomic next-generation sequencingpathogenics

Identifiers

PMID40109771
PMCPMC11920761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.