Evidence map›Paper›PMID 40109675›Full record

ArticleJournal of food science and technology2025

Sesame defatted flour: antioxidant response and improvement in carbohydrate metabolism in high-fructose/high-saturated fatty acids diet-fed mice.

Agustín Lucini Mas, Alejandra Mariel Canalis, Mara Soledad Mattalloni, María Eugenia Pasqualini, Daniel Alberto Wunderlin, María Verónica Baroni

Abstract read
In one paragraph

Article in Journal of food science and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Agustín Lucini MasInstituto de Ciencia y Tecnología de Alimentos Córdoba. (ICYTAC-CONICET) SeCyT, Universidad Nacional de Córdoba, Córdoba, Argentina.
Alejandra Mariel CanalisInstituto de Ciencia y Tecnología de Alimentos Córdoba. (ICYTAC-CONICET) SeCyT, Universidad Nacional de Córdoba, Córdoba, Argentina.
Mara Soledad MattalloniInstituto de Ciencia y Tecnología de Alimentos Córdoba. (ICYTAC-CONICET) SeCyT, Universidad Nacional de Córdoba, Córdoba, Argentina.
María Eugenia PasqualiniInstituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET). Pabellón Biología Celular, Universidad Nacional de Córdoba, Córdoba, Argentina.
Daniel Alberto WunderlinInstituto de Ciencia y Tecnología de Alimentos Córdoba. (ICYTAC-CONICET) SeCyT, Universidad Nacional de Córdoba, Córdoba, Argentina.
María Verónica BaroniInstituto de Ciencia y Tecnología de Alimentos Córdoba. (ICYTAC-CONICET) SeCyT, Universidad Nacional de Córdoba, Córdoba, Argentina.ORCID 0000-0001-9316-7907

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the effect of dietary supplementation with defatted sesame seeds on a diet with low nutritional quality (high-fructose and high proportion of saturated fatty acids), in terms of the redox state and carbohydrate metabolism. C57BL/6 male mice were fed for 12 weeks with Control (C), Low Nutritional Quality (LNQ), or supplemented with sesame defatted flour (LNQ + S) diets. Levels of glucose, lactate, reactive oxygen species, antioxidant enzyme activity, reduced glutathione, and protein oxidation (AOPP) were determined. Overall, LNQ increased liver glucose (+ 20%), lactate (+ 60%) and AOPP (+15%) with respect to C, and modulated the enzymatic and non-enzymatic endogenous antioxidants. However, sesame supplementation restored glucose and lactate levels to those of C group and modulated the endogenous antioxidant systems, contributing to a reduction in oxidative damage in proteins. In conclusion, supplementation with sesame showed beneficial effects in mice fed a low nutritional quality diet. Supplementary Information: The online version contains supplementary material available at 10.1007/s13197-024-06049-2.

Indexed as

AntioxidantCarbohydrate metabolismFructoseOxidative stressPolyphenolsSaturated fatty acidsSesame

Identifiers

PMID40109675
PMCPMC11914681

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.