Evidence map›Paper›PMID 40109673›Full record

ArticleOptica2024

Asynchronous, semi-reverberant elastography.

Ginger Schmidt, Brett E Bouma, Néstor Uribe-Patarroyo

Abstract read
In one paragraph

Article in Optica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ginger SchmidtWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.ORCID 0000-0003-4373-3266
Brett E BoumaWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.
Néstor Uribe-PatarroyoWellman Center for Photomedicine, Harvard Medical School and Massachusetts General Hospital, 40 Blossom Street, Boston, Massachusetts 02114, USA.ORCID 0000-0001-9201-2196

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Benjamin James Vakoc · 2012 to 2026
$22.4M
Intravascular microstructural, chemical and biomechanical characterization of coronary plaquesR01EB033306 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI URIBE-PATARROYO, NESTOR · 2022 to 2025
$2.5M
Blood flow-based guidance and diagnostics using OCTK25EB024595 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI URIBE-PATARROYO, NESTOR · 2017 to 2021
$825k
NIBIB NIH HHS K25 EB024595NIBIB NIH HHS P41 EB015903NIBIB NIH HHS R01 EB033306
6 · The paper itself

Abstract

Optical coherence elastography measures elasticity-a property correlated with pathologies such as tumors due to fibrosis, atherosclerosis due to heterogeneous plaque composition, and ocular diseases such as keratoconus and glaucoma. Wave-based elastography, including reverberant elastography, leverages the properties of shear waves traveling through tissue primarily to infer shear modulus. These methods have already seen significant development over the past decade. However, existing implementations in OCT require robust synchronization of shear wave excitation with imaging, complicating widespread clinical adoption. We present a method for complete recovery of the harmonic shear wave field in an asynchronous, conventional frame-rate, raster-scanning OCT system by modeling raster-scanning as an amplitude modulation of the displacement field. This technique recovers the entire spatially and temporally coherent complex valued shear wave field from just two B-scans, while reducing the time scale for sensitivity to motion from minutes to tens of milliseconds. To the best of our knowledge, this work represents the first successful demonstration of reverberant elastography on a human subject

Identifiers

PMID40109673
PMCPMC11922557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.