Evidence map›Paper›PMID 40109486›Full record

ReviewJAACAP open2025

Review: Evidence-Based Psychosocial Treatments for Childhood Irritability and Aggressive Behavior.

Carla B Kalvin, Julia Zhong, Megan R Rutten, Karim Ibrahim, Denis G Sukhodolsky

Abstract readReview
In one paragraph

Review in JAACAP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carla B KalvinYale University School of Medicine, Child Study Center, New Haven, Connecticut.
Julia ZhongYale University School of Medicine, Child Study Center, New Haven, Connecticut.
Megan R RuttenYale University School of Medicine, Child Study Center, New Haven, Connecticut.
Karim IbrahimYale University School of Medicine, Child Study Center, New Haven, Connecticut.
Denis G SukhodolskyYale University School of Medicine, Child Study Center, New Haven, Connecticut.

Funding

Subnetwork-based Quantitative Imaging Biomarkers for Therapy Assessment in AutismR01NS035193 · NINDS · YALE UNIVERSITY · PI JAMES S DUNCAN, LAWRENCE H. STAIB · 1996 to 2026
$9.2M
Using CBT to examine circuitry of frustrative non-reward in aggressive childrenR01MH101514 · NIMH · YALE UNIVERSITY · PI PELPHREY, KEVIN A, SUKHODOLSKY, DENIS G · 2013 to 2016
$1.8M
NIMH NIH HHS R01 MH101514NINDS NIH HHS R01 NS035193
6 · The paper itself

Abstract

Objective: Irritability and aggression are among the most common reasons that children are referred to outpatient mental health services and represent symptoms of several child psychiatric disorders. Over the past 40 years, several types of psychosocial interventions have been developed to treat these problems. This review examines well-established interventions for childhood irritability and aggression as well as newer interventions with a growing evidence base. Method: This is a narrative review of evidence-based psychosocial treatments for childhood irritability and maladaptive aggression highlighting the key principles, techniques, and assessment tools as relevant to clinical practice. Results: Parent management training and cognitive-behavioral therapy both have extensive evidence bases and are recognized as efficacious interventions for childhood aggression and disruptive behavior. There is also accumulating evidence that these modalities as well as dialectical behavior therapy can be helpful for irritability in the context of severe mood dysregulation and disruptive mood dysregulation disorder. Technology-based and telehealth interventions for childhood aggression and irritability show promising results and potential to improve access to services. Lastly, measurement-based care, while still a developing area in child mental health, may provide a promising addition to enhancing the efficacy and precision of psychosocial treatments of childhood aggression and irritability. Conclusion: Parent- and child-focused psychosocial interventions such as parent management training, cognitive-behavioral therapy, and their combination can be helpful for the reduction of irritability and aggression. Well-powered randomized controlled trials with outcome measures that reflect current conceptualization of maladaptive aggression and irritability are needed to extend this evidence base to older adolescents and to examine the role of co-occurring psychopathology in treatment response.

Indexed as

aggressionevidence-basedirritabilitypsychosocial treatment

Identifiers

PMID40109486
PMCPMC11914907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.