Evidence map›Paper›PMID 40109485›Full record

ArticleJAACAP open2025

Attention-Deficit/Hyperactivity Disorder Symptoms and Anger and Aggression in Russian Adolescents.

Johan Isaksson, Denis G Sukhodolsky, Roman Koposov, Andrew Stickley, Mia Ramklint, Vladislav Ruchkin

Abstract read
In one paragraph

Article in JAACAP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johan IsakssonUppsala University, Uppsala, Sweden.
Denis G SukhodolskyYale University School of Medicine, New Haven, Connecticut.
Roman KoposovThe Arctic University of Norway, Tromsö, Norway, and Sechenov First Moscow State Medical University, Moscow, Russia.
Andrew StickleySödertörn University, Sweden, and National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Mia RamklintUppsala University, Uppsala, Sweden.
Vladislav RuchkinUppsala University, Uppsala, Sweden.

Funding

Subnetwork-based Quantitative Imaging Biomarkers for Therapy Assessment in AutismR01NS035193 · NINDS · YALE UNIVERSITY · PI JAMES S DUNCAN, LAWRENCE H. STAIB · 1996 to 2026
$9.2M
EEG coherence in children with TS: Association with ADHD and tic severityR03MH094583 · NIMH · YALE UNIVERSITY · PI SUKHODOLSKY, DENIS G · 2012 to 2013
$163k
NIMH NIH HHS R03 MH094583NINDS NIH HHS R01 NS035193
6 · The paper itself

Abstract

Objective: Aggression is a multifaceted behavior that involves cognitive, behavioral, and affective components. Although aggressive behaviors are commonly observed among individuals with attention-deficit/hyperactivity disorder (ADHD), potential sex-specific aspects of the association between ADHD symptoms and different components of aggression need to be evaluated, while also controlling for comorbid problems. Method: In the present cross-sectional study, self-reported data were collected from 2,838 adolescents (mean age = 14.89 years) from Russia on ADHD symptoms and cognitive (anger rumination, aggressive beliefs), behavioral (physical, verbal, social, proactive), and affective (trait anger) aspects of aggression as well as comorbid emotional and conduct problems. Generalized linear model analyses were used to examine the associations between ADHD symptoms and aggression and to explore sex differences, while also adjusting for comorbid problems. Results: Clinically significant levels of ADHD symptoms were associated with all components of aggression, and the associations remained significant after adjusting for emotional and conduct problems. Overall, females had higher levels of trait anger and anger rumination, whereas males had higher levels of aggressive beliefs, proactive aggression, and physical and verbal aggression. There was also a sex-specific association, where males with ADHD symptoms reported higher levels of social aggression. Conduct problems moderated the association between ADHD and aggression, increasing the likelihood of trait anger and social aggression in adolescents without ADHD symptoms. Conclusion: Clinically significant levels of ADHD symptoms seem to impact all components of aggression independent of comorbidity. It is therefore important to consider aggression when evaluating and treating ADHD.

Indexed as

ADHDaggressionangercomorbiditysex differences

Identifiers

PMID40109485
PMCPMC11914921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.