Evidence map›Paper›PMID 40109470›Full record

ReviewSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2025

[Role of Traditional Chinese Medicine in Pathogen-Induced Metabolic Reprogramming and Immune Suppression].

Yixiong Dang, Xin Sun, Jingwen Jiang

Abstract readReviewEnglish Abstract
In one paragraph

Review in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yixiong Dang/ ( 610041) West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Xin Sun/ ( 610041) West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Jingwen Jiang/ ( 610041) West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Chinese medicine (TCM), an essential component of the traditional medicine practiced in China, has demonstrated unique therapeutic efficacy in combating infectious diseases caused by pathogens and various types of tumors. In particular, TCM plays a vital role in enhancing immune function, maintaining homeostasis, and improving metabolic balance. However, the complex ingredients used in TCM and its broad range of therapeutic targets present challenges for comprehensive analysis of the mechanisms involved. Moreover, the molecular and cellular mechanisms underlying TCM's effects remain underexplored, limiting its broader application in modern medicine. Recent studies have increasingly revealed that TCM can not only directly inhibit the activity of pathogens, such as bacteria, fungi, viruses, and tumor cells, but also exert profound effects on immune remodeling by regulating the metabolism of both pathogens and hosts. Therefore, a comprehensive understanding of the role of TCM in metabolic regulation is crucial for elucidating its anti-pathogenic effects. This review is focused on the metabolic pathways of pathogens and host metabolic reprogramming induced by pathogens. We systematically reviewed the mechanisms by which TCM regulates pathogen metabolism, influences pathogen-induced metabolic reprogramming in hosts, and mitigates immune suppression caused by pathogens. This review may provide new ideas for investigating the molecular mechanisms of TCM in disease development and progression.

Indexed as

Drugs, Chinese HerbalMedicine, Chinese TraditionalAnimalsHumansMetabolic Networks and PathwaysMetabolic ReprogrammingDrugs, Chinese HerbalImmunityMetabolic reprogrammingMolecular mechanismsPathogensReviewTraditional Chinese medicine

Identifiers

PMID40109470
PMCPMC11914019

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.