Evidence map›Paper›PMID 40109353›Full record

ArticleNAR genomics and bioinformatics2025

Crafted experiments to evaluate feature selection methods for single-cell RNA-seq data.

Siyao Liu, David L Corcoran, Susana Garcia-Recio, James S Marron, Charles M Perou

Abstract read
In one paragraph

Article in NAR genomics and bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siyao LiuLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, United States.ORCID 0000-0002-7919-9184
David L CorcoranLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, United States.
Susana Garcia-RecioLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, United States.
James S MarronLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, United States.
Charles M PerouLineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, United States.ORCID 0000-0001-9827-2247

Funding

Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHARLES M PEROU · 1992 to 2026
$59.3M
Breast Cancer Research Foundation RO1-CA14876National Cancer Institute (NCI) Breast Cancer Specialized Program of Research Excellence (SPORE) program P50-CA58223National Science Foundation DMS-2113404NCI NIH HHS P50 CA058223
6 · The paper itself

Abstract

While numerous methods have been developed for analyzing scRNA-seq data, benchmarking various methods remains challenging. There is a lack of ground truth datasets for evaluating novel gene selection and/or clustering methods. We propose the use of

Indexed as

RNA-SeqSequence Analysis, RNASingle-Cell AnalysisSoftwareAlgorithmsHumansSingle-Cell Gene Expression Analysis

Identifiers

PMID40109353
PMCPMC11920870

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.