Evidence map›Paper›PMID 40109350›Full record

ArticleFrontiers in immunology2025

Complete response of advanced esophageal squamous cell carcinoma with first-line chemotherapy combined with immunotherapy: a Case report.

Yahong Wei, Shaohui Han, Yabin Shi, Yaxing Li, Qi Zhang, Lijuan Zhang, Yan Cheng, Xiaolu Yan, Yitao Jia

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yahong WeiDepartment of Chemotherapy Center, Hebei General Hospital, Shijiazhuang, Hebei, China.
Shaohui HanDepartment of Thoracic Surgery, Hebei General Hospital, Shijiazhuang, Hebei, China.
Yabin ShiDepartment of Pathology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Yaxing LiDepartment of Chemotherapy Center, Hebei General Hospital, Shijiazhuang, Hebei, China.
Qi ZhangDepartment of Chemotherapy Center, Hebei General Hospital, Shijiazhuang, Hebei, China.
Lijuan ZhangDepartment of Chemotherapy Center, Hebei General Hospital, Shijiazhuang, Hebei, China.
Yan ChengDepartment of Chemotherapy Center, Hebei General Hospital, Shijiazhuang, Hebei, China.
Xiaolu YanDepartment of Oncology, Hebei General Hospital, Shijiazhuang, Hebei, China.
Yitao JiaDepartment of Oncology, Hebei General Hospital, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC) is a prevalent and aggressive malignancy, often diagnosed at an advanced stage with poor prognosis. This case report highlights the successful treatment of a patient with advanced ESCC, who presented with bilateral lung and adrenal gland metastases. Despite the aggressive nature of the disease, the patient underwent a regimen of first-line chemotherapy combined with immunotherapy, followed by immune maintenance therapy. Remarkably, the patient achieved complete remission after the completion of treatment, demonstrating the potential efficacy of this combined therapeutic approach in managing advanced ESCC with multiple metastatic sites.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaImmunotherapyAdrenal Gland NeoplasmsHumansLung NeoplasmsTreatment Outcomeadvanced cancerchemotherapycomplete responseesophageal squamous cell carcinoma (ESCC)immunotherapy

Identifiers

PMID40109350
PMCPMC11920187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.