Evidence map›Paper›PMID 40109230›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025

Survivorship issues in long-term survivors of locally recurrent rectal cancer: A qualitative study.

Niamh McKigney, Sophia Waldenstedt, Elisabeth Gonzalez, Jan M van Rees, Henriette Vind Thaysen, Eva Angenete, Galina Velikova, Julia M Brown, Deena P Harji, LRRC‐QoL Collaborators

Abstract readMulticenter Study
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Survivorship issues in long-term survivors of locally recurrent rectal cancer: A qualitative study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Niamh McKigneyClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.ORCID 0000-0003-1599-5701
Sophia WaldenstedtDepartment of Surgery, SSORG-Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-2181-1625
Elisabeth GonzalezDepartment of Surgery, SSORG-Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jan M van ReesDepartment of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, University Hospital Rotterdam, Rotterdam, The Netherlands.
Henriette Vind ThaysenDepartment of Surgery, Aarhus University Hospital, Aarhus, Denmark.
Eva AngeneteDepartment of Surgery, SSORG-Scandinavian Surgical Outcomes Research Group, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0001-9966-4904
Galina VelikovaLeeds Institute of Medical Research at St James's, University of Leeds, St James's University Hospital, Leeds, UK.
Julia M BrownClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
Deena P HarjiClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
LRRC‐QoL Collaborators

Funding

ALFGBG 965084Anna-Lisa and Bror Bjornssons FoundationBowel Research UKCancerfondenPelican Cancer FoundationStiftelsen Assar Gabrielssons FondSwedish Cancer Society 22 2265 Pj
6 · The paper itself

Abstract

aimThere are increasing numbers of long-term survivors following curative treatment for locally recurrent rectal cancer (LRRC); however, their experiences remain relatively underreported. The aim of this qualitative study was to identify the long-term survivorship issues relevant to these patients.

methodAdults who remained disease free >3 years following treatment for LRRC were invited to participate in an international multicentre study. Semistructured qualitative interviews were conducted either in person, via telephone or via Microsoft Teams and were analysed using a framework method of thematic analysis.

resultsA total of 26 participants were recruited from 11 sites in seven countries. Sixteen (61.5%) participants were male, the median age was 70.5 (33.0-85.0) years, participants were a median of 5.0 (3.0-17.0) years posttreatment, most had undergone surgery for LRRC (n = 24, 92.3%), two participants received neoadjuvant chemo/radiation for LRRC with a complete response. Eight major survivorship themes were identified: (1) experience of long-term follow-up care, (2) unmet needs and areas for improvement, (3) long-term physical effects of cancer and treatment, (4) living with a stoma, urostomy or other urinary device, (5) long-term psychological impact, (6) impact on sexual function and intimate relationships, (7) impact on daily life and (8) feelings surrounding life now, adapting and the future.

conclusionParticipants experienced a wide range of long-term survivorship issues, reflecting the complexity of both LRRC and its treatment. Despite this, most had adapted well. Further work regarding survivorship care in LRRC is required to address the unmet needs and issues highlighted in this study, such as support regarding sexual function.

Indexed as

Cancer SurvivorsNeoplasm Recurrence, LocalRectal NeoplasmsSurvivorshipAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedQualitative ResearchQuality of Lifelocally recurrent rectal cancerlong‐term survivorshipunmet needs

Identifiers

PMID40109230
PMCPMC11923726

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.