ArticleCurrent pharmaceutical design2025
Green Synthesis of Curcumin Loaded Carbon Dots as a Sustained Drug Delivery for Anticancer Therapy.
Article in Current pharmaceutical design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Carbon-Based Nanoplatforms in Diabetes: A New Paradigm in Diagnosis and Treatment.Annals of biomedical engineering · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo enhance curcumin's bioavailability with the help of carbon dot and piperine, due to its promising anticancer activity.
backgroundCancer is a disease condition, where some cells grow uncontrollably, and if not controlled, they spread to other parts of the body. Concerning anticancer agents, curcumin has anticancer properties along with anti-inflammatory, antimicrobial, and antioxidant. Here in this study, the pharmacokinetic property was improved with the help of Carbon Dot encapsulation.
methodsBamboo leaves were used for the preparation of CDs and curcumin was loaded in them and the characterization for particle size, morphology, loading capacity, quantum yield, drug release in vitro studies, and
resultsPrepared CDs have a smaller particle size (< 10 nm), good loading capacity, stability, and excellent fluorescence activity. Studies on the release of curcumin have shown that a pH-5.5 solution leads to enhanced curcumin release. The CDs-curcumin shows enhanced toxicity against cancerous cells than the curcumin even at lower concentrations (20, 40, 60, 80, 100 μM).
conclusionCurcumin can be delivered by CDs, which have the advantages of increased bioavailability, small size, high loading capacity, improved photoluminescence, and biocompatibility. These characteristics can result in improved anticancer activities even at low concentrations.
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Registered trials
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