Evidence map›Paper›PMID 40108719›Full record

Observational studyCritical care (London, England)2025

Clinical outcomes and peripheral tissue oxygen saturation monitoring of the knee region by near-infrared spectroscopy in circulatory shock: a prospective observational cohort study.

Elina Varis, Maria Heliste, Johanna Hästbacka, Suvi T Vaara, Markus B Skrifvars, Ville Pettilä, Mitja Lääperi, Anne Kuitunen, Annukka Vahtera, Erika Wilkman

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03814564 (ASSESSment of Peripheral Perfusion, Tissue Oxygen Saturation, Endothelial Function and Coagulation Disorder in Circulatory SHOCK, the ASSESS - SHOCK Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03814564 completednot on this map

ASSESSment of Peripheral Perfusion, Tissue Oxygen Saturation, Endothelial Function and Coagulation Disorder in Circulatory SHOCK, the ASSESS - SHOCK Study

TypeobservationalSponsorHelsinki University Central HospitalRan2019 to 2023Enrolled325ConditionsCirculatory FailureArmsNIRS monitoring
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elina VarisHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland. elina.varis@hus.fi.
Maria HelisteHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland.
Johanna HästbackaFaculty of Medicine and Health Technology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, and Tampere University, Tampere, Finland.
Suvi T VaaraHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland.
Markus B SkrifvarsHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland.
Ville PettiläHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland.
Mitja LääperiLääperi Statistical Consulting, Espoo, Finland.
Anne KuitunenFaculty of Medicine and Health Technology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, and Tampere University, Tampere, Finland.
Annukka VahteraFaculty of Medicine and Health Technology, Tampere University Hospital, Wellbeing Services County of Pirkanmaa, and Tampere University, Tampere, Finland.
Erika WilkmanHelsinki University Hospital (Perioperative and Intensive Care), University of Helsinki, Helsinki, Finland.

Funding

Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2020341
6 · The paper itself

Abstract

backgroundIn circulatory shock, tissue hypoperfusion leads to adverse outcomes. We hypothesized that peripheral tissue oxygen saturation (StO

methodsASSESS-SHOCK was a prospective, observational study enrolling circulatory shock patients from April 2019 to May 2023 in three intensive care units (ICU). Adult patients fulfilling the criteria for circulatory shock within 24 h of ICU admission were eligible. Patients underwent continuous 48 h StO

resultsWe included 256 patients. Due to several reasons, including the COVID-19 pandemic, the patient sample was not consecutive. The median of 48-h mean StO

conclusionsLower peripheral StO

trial registrationClinicalTrials.gov Identifier: NCT03814564, registered 15 January 2019.

Indexed as

KneeOxygenOxygen SaturationShockAgedCohort StudiesCOVID-19FemaleHumansIntensive Care UnitsMaleMiddle AgedMonitoring, PhysiologicOrgan Dysfunction ScoresProspective StudiesSpectroscopy, Near-InfraredOxygenCirculatory shockNear-infrared spectroscopyTissue oxygen saturationTissue perfusion

Identifiers

PMID40108719
PMCPMC11924835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.