Evidence map›Paper›PMID 40108679›Full record

ArticleEuropean journal of medical research2025

Effects of different pulse widths on acute tibial nerve stimulation for overactive bladder in cats.

Dongsheng Shang, Haoyu Sun, Han Deng, Gongyue Liu, Limin Liao, Xing Li

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dongsheng ShangDepartment of Rehabilitation, The Second Affiliated Hospital and Yuying Children'S Hospital of Wenzhou Medical University, Wenzhou, China.
Haoyu SunDepartment of Urology, Rehabilitation School of Capital Medical University, China Rehabilitation Research Center, Beijing, China.
Han DengDepartment of Urology, Rehabilitation School of Capital Medical University, China Rehabilitation Research Center, Beijing, China.
Gongyue LiuDepartment of Urology, Rehabilitation School of Capital Medical University, China Rehabilitation Research Center, Beijing, China.
Limin LiaoDepartment of Rehabilitation, The Second Affiliated Hospital and Yuying Children'S Hospital of Wenzhou Medical University, Wenzhou, China.
Xing LiDepartment of Rehabilitation, The Second Affiliated Hospital and Yuying Children'S Hospital of Wenzhou Medical University, Wenzhou, China. lxurology@126.com.

Funding

Natural Science Foundation of Beijing Municipality 7222235
6 · The paper itself

Abstract

purposeThis study aimed to assess the effectiveness of different pulse widths in suppressing bladder overactivity using tibial nerve stimulation (TNS) in cats.

methodsHook electrodes were implanted on the left tibial nerve. Cystometry was conducted by infusing either acetic acid (AA) or normal saline (NS). TNS was applied at intensities of 2-4 times the threshold (T) with pulse widths ranging from 60 to 624 µsec. Cystometrograms were used to evaluate the impact of different pulse widths on the micturition reflex.

resultsBladder capacity (BC) was significantly reduced to 49.71% ± 6.76% of the NS control level (8.58 ± 1.70 mL) due to AA-induced bladder overactivity (P < 0.001). During AA infusion, TNS at pulse widths of 60, 210, 420, and 624 µsec significantly increased BC to 70.65% ± 9.06%, 73.22% ± 6.28%, 73.79% ± 8.56%, and 76.25% ± 7.95% of the NS control level, respectively (P < 0.001). No significant differences were observed among the four pulse widths (P > 0.05). The threshold intensity (T) was higher at 60 µsec than at 624 µsec (P < 0.01), while T at 210 µsec, 420 µsec, and 624 µsec showed no significant differences (P > 0.05).

conclusionsAll four pulse widths demonstrated inhibitory effects on bladder overactivity. However, no significant differences were observed among the four pulse widths.

Indexed as

Electric Stimulation TherapyTibial NerveUrinary Bladder, OveractiveAnimalsCatsFemaleUrinary BladderUrinationCatsCystometryOveractive bladderPulse widthsTibial nerve stimulation

Identifiers

PMID40108679
PMCPMC11921490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.