ArticleBMC psychiatry2025
Exploring generalized anxiety disorder symptoms: key insights from a population-based study in Iran.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Towards Mechanism-Informed Treatments for Mental Health.Journal of neurochemistry · 2026Review
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7 authors.
Funding
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Abstract
aimGeneralized Anxiety Disorder (GAD) is a common mental health condition with considerable impacts on both individuals and society, associated with high healthcare costs and reduced quality of life. Linked to a range of genetic, psychological, and social factors, GAD also frequently coexists with other mental health conditions. This study investigates the socio-demographic, environmental, and psychosocial risk factors for GAD symptoms in an urban Iranian population, addressing a key research gap and guiding targeted interventions.
methodA cross-sectional study was conducted to determine the prevalence and associated factors of GAD symptoms among adults in Tehran. Using multi-stage sampling, participants completed questionnaires on socio-demographic characteristics, recent stressors, and DSM-5 criteria for GAD. Descriptive statistics identified prevalence patterns, and logistic regression models evaluated associations and adjusted for confounders (p < 0.05). Analyses were conducted in STATA v.14, with adjusted odds ratios and 95% confidence intervals reported.
resultsOf 970 participants, 26% met criteria for GAD (CI 95%: 22%-32%). Individuals with GAD were more likely to be single, dissatisfied with life, of low socioeconomic status, and to report non-healthy status and recent stressors. In multivariable regression, significant risk factors for GAD included female gender (AOR = 1.4, p < 0.01), experiencing at least one recent stressful event (AOR = 1.9, p = 0.01), and poor health status (AOR = 2.8, p < 0.05).
conclusionThis study highlights the prevalence of GAD symptoms in Tehran and underscores the critical roles of policymakers and healthcare providers in addressing it. Effective management requires a multifaceted approach, including individual treatment, social integration, and community support. Future research should focus on culturally sensitive interventions and awareness campaigns to reduce stigma. Overall, the study enriches the literature on GAD in Iran and encourages collaborative efforts to enhance mental health outcomes and community well-being.
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