ArticleNature2025
Matrix-producing neutrophils populate and shield the skin.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.
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42citing papers in PubMed
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Who cites it
42 citing papers in PubMed.
- Neutrophils: The Overlooked Regenerative Role in Bone Repair.Stem cell reviews and reports · 2026Review
- A skin-kidney neutrophil axis links ultraviolet exposure to renal angiogenesis and tissue remodeling in healthy and lupus kidneys.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- Targeting the immune-metabolic axis reverses orthodontics-induced systemic pathology.Signal transduction and targeted therapy · 2026Article
- Mechanoregulative hydrogel enables scar-reduced and functional healing of infected diabetic mobile wounds.Materials today. Bio · 2026Article
- Macrophage regulation of extracellular matrix remodeling in aging skeletal muscle.Ageing research reviews · 2026Review
- Mechanical regulation of immunity in metastasis.Nature materials · 2026Article
- Tissue-resident neutrophils serve homeostatic and immunological functions in embryos.Nature communications · 2026Article
- Threat assessment shapes neutrophil cell fate upon inflammasome activation.Science advances · 2026Article
- Pathogenic role of serpin B3-positive neutrophils in reinforcing thrombus stiffening during ischemic stroke.Blood · 2026Article
- Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions.International wound journal · 2026Review
- Transient immunostimulation with LPS promotes tissue repair in aged skin.Immunity & ageing : I & A · 2026Article
- Research progress on the mechanisms of Panax ginseng and its active components in maintaining skin homeostasis and disease intervention.Chinese medicine · 2026Review
- Enrichment of HLA-DRiScience · 2026Article
- Myeloperoxidase promotes fibrosis by inhibiting cathepsin K to bias the lung toward ECM accumulation.bioRxiv : the preprint server for biology · 2026Article
- Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity.Nature immunology · 2026Article
- Structural immunity: immune cells as architects of tissue barriers.Nature reviews. Immunology · 2026Review
- Approaching Scarless Wound Healing: From Passive Anti-Fibrotic to Proactive and Programmable Pro-Regenerative Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- DNA-Inspired Multi-Functional Double-Cross-Linking Self-Healing Hydrogel Promotes the Healing of Diabetic Wounds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Enhanced Alarmin Secretion Exacerbates Neutrophil Extracellular Trap (NET) Formation in Active Psoriasis: Implication of IL-33 and TSLP in Driving NET Formation, Inflammation and Oxidative Stress in Psoriasis.Antioxidants (Basel, Switzerland) · 2026Article
- Harnessing neutrophils for tissue repair and regeneration: mechanisms, biomaterial engineering strategies and translational potential.Regenerative biomaterials · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
38 authors.
Tommaso Vicanolo *Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Alaz Özcan *Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Jackson LiangYao Li *Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0001-5197-193X
Carla Huerta-LópezCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-6943-3475
Iván BallesterosCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-6246-2353
Andrea Rubio-PonceCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Andra C DumitruCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-3574-0992
Jose Ángel Nicolás-ÁvilaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-8301-7216
Miguel Molina-MorenoVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-3493-7470
Pablo Reyes-GutierrezVascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Andrew D JohnstonDepartment of Dermatology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5769-3106
Catherine MartoneDepartment of Genetics, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0003-0633-1559
Eric GretoDepartment of Internal Medicine 3-Rheumatology and Immunology, Deutsches Zentrum für Immuntherapie (DZI), Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
Antonio Quílez-AlvarezCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Enrique CalvoCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0001-9096-5233
Elena Bonzon-KulichenkoCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-0852-7520
Rebeca Álvarez-VelezCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-5286-4500
Ming Yao ChooiSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Immanuel KwokSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Blanca González-BermúdezCenter for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.ORCID 0000-0002-1266-0917
Benoit MalleretSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.ORCID 0000-0001-9658-7528
Francisco M EspinosaInstituto de Ciencia de Materiales de Madrid, CSIC, Madrid, Spain.
Ming ZhangDepartment of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yu-Long WangDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0002-3830-7257
Dasheng SunOPO and Organ Transplantation Leading Group, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shu Zhen ChongSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Republic of Singapore.
Ali El-ArmoucheInstitute of Pharmacology and Toxicology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Kevin K KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Irina A UdalovaKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.ORCID 0000-0002-6716-2528
Valentina GrecoDepartment of Genetics, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-6492-4603
Ricardo GarciaInstituto de Ciencia de Materiales de Madrid, CSIC, Madrid, Spain.ORCID 0000-0002-7115-1928
Jesús VázquezCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0003-1461-5092
Ana DopazoCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.ORCID 0000-0002-4910-1684
Gustavo R PlazaInstituto de Ciencia de Materiales de Madrid, CSIC, Madrid, Spain.ORCID 0000-0002-5555-5498
Jorge Alegre-CebolladaCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.
Stefan UderhardtDepartment of Internal Medicine 3-Rheumatology and Immunology, Deutsches Zentrum für Immuntherapie (DZI), Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany. Stefan.uderhardt@fau.de.ORCID 0000-0002-2489-2109
Lai Guan NgShanghai Immune Therapy Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. nglaiguan@renji.com.ORCID 0000-0003-1905-3586
Andrés HidalgoCentro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain. andres.hidalgo@yale.edu.ORCID 0000-0001-5513-555X
Funding
Non-canonical functions of neutrophilsR01AI165661 · NIAID · YALE UNIVERSITY · PI HIDALGO, ANDRES · 2022 to 2025
$2.8MOxidized Phospholipids Derived from Apoptotic Pneumocytes Drives Macrophage Activation and Initiates Lung FibrosisR01HL153056 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KIM, KEVIN KEEWOUN, SISSON, THOMAS H · 2021 to 2024
$2.5MTargeting Fibroblast Discoidin Domain Receptor 2 for Immunotherapy to Pulmonary FibrosisR01HL156998 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KESHAMOUNI, VENKATESHWAR G, KIM, KEVIN KEEWOUN · 2022 to 2025
$2.4MNHLBI NIH HHS R01 HL153056NHLBI NIH HHS R01 HL156998NIAID NIH HHS R01 AI165661Wellcome Trust
Abstract
Defence from environmental threats is provided by physical barriers that confer mechanical protection and prevent the entry of microorganisms
Indexed as
Extracellular MatrixNeutrophilsSkinAnimalsFemaleHumansImmunity, InnateMaleMiceSignal TransductionTransforming Growth Factor betaWound HealingTransforming Growth Factor beta
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.