Evidence map›Paper›PMID 40108461›Full record

ArticleNature2025

Overlapping nuclear import and export paths unveiled by two-colour MINFLUX.

Abhishek Sau, Sebastian Schnorrenberg, Ziqiang Huang, Debolina Bandyopadhyay, Ankith Sharma, Clara-Marie Gürth, Sandeep Dave, Siegfried M Musser

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Structure, function and assembly of nuclear pore complexes.Nature reviews. Molecular cell biology · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
  18. Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abhishek SauDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-5560-5360
Sebastian SchnorrenbergEMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID 0000-0002-8076-2237
Ziqiang HuangEMBL Imaging Centre, European Molecular Biology Laboratory, Heidelberg, Germany.
Debolina BandyopadhyayDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX, USA.
Ankith SharmaDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX, USA.ORCID 0000-0002-0724-5444
Clara-Marie GürthAbberior Instruments GMBH, Göttingen, Germany.
Sandeep DaveDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX, USA.
Siegfried M MusserDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX, USA. smusser@tamu.edu.ORCID 0000-0002-7793-2557

Funding

Mapping Transport Pathways through Nuclear Pores using 3D Super-Resolution MicroscopyR01GM126190 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MUSSER, SIEGFRIED M · 2018 to 2025
$2.6M
Time-Resolved Confocal Fluorescence Microscope with Single Molecule SensitivityS10OD032208 · OD · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI MUSSER, SIEGFRIED M · 2022 to 2022
$600k
NIGMS NIH HHS R01 GM126190NIH HHS S10 OD032208
6 · The paper itself

Abstract

The nuclear pore complex (NPC) mediates nucleocytoplasmic exchange, catalysing a massive flux of protein and nucleic acid material in both directions

Indexed as

Active Transport, Cell NucleusCell NucleusEukaryotic CellsNuclear PoreSingle Molecule ImagingAnimalsCell LineHumansPhotobleachingSpatio-Temporal Analysis

Identifiers

PMID40108461
PMCPMC12003200

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.