ArticleScientific reports2025
A new concept and surgical approach for Chiari malformation type I based on the protection and strengthening of the myodural Bridge.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From gene to geometry: the molecular morphogenesis of the fourth ventricle angle and its role in predicting brainstem dysfunction among Chiari I malformation patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- The myodural bridge complex: a comprehensive review of morphology, physiology, developmental biology and pathology.Frontiers in medicine · 2026Review
- Temporal and spatial variations in CSF pressure are influenced by electrical stimulation of the OCI muscles in beagles.Scientific reports · 2025Article
- Force-dependent development of the myodural bridge in rats: The impact of Integrin α7.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Chiari malformation type I (CM-I) is the most common subtype of Chiari malformation which can lead to brainstem compression and alterations in cerebrospinal fluid (CSF) flow. Common complications in patients undergoing traditional surgical approach include pseudomeningocele, CSF leak, and exacerbation of symptoms. The authors present a new minimally invasive surgery technique for protection and strengthening of the myodural bridge (MDB) in order to prevent the postoperative complications. A retrospective study was performed on 55 CM-I patients undergoing surgical treatment from January 2019 to April 2024 in a center. These patients underwent the surgical procedure of either posterior fossa decompression with duraplasty and tonsillar coagulation (PFDDC) or PFDDC with protection and strengthening of the MDB (PFDDC + MDB). The clinical outcomes and complications of the two procedures. 29 patients underwent PFDDC, and 26 patients underwent PFDDC + MDB. Overall complications rates were significantly reduced in the PFDDC + MDB group (3.8% vs. 34.5%, P = 0.012). Meningitis was observed in 3 (10.3%) in the PFDDC group and 1 (3.8%) in the PFDDC + MDB group (P = 0.613). Pseudomeningocele was more frequent in the PFDDC group than in the PFDDC + MDB group (24.1% vs. 0%, P = 0.011). No patient required a revision operation. There were no statistical differences in symptom improvement between the two groups. PFDDC + MDB seems to be a safe and effective treatment for CM-I patients with or without syringomyelia. This new procedure can bring clinical improvement and lower complication rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.