Evidence map›Paper›PMID 40108182›Full record

ArticleScientific reports2025

Development of machine learning-based differential diagnosis model and risk prediction model of organ damage for severe Mycoplasma pneumoniae pneumonia in children.

Bing He, Xuewen Li, Rongrong Dong, Han Yao, Qi Zhou, Changyan Xu, Chengming Shang, Bo Zhao, Huiling Zhou, Xinqiao Yu and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Machine learning-based prediction models for severeFrontiers in public health · 2026
    Pooled it
  2. Research progress on detection technologies for Mycoplasma pneumoniae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Development of a Prediction Model for Severe PediatricInfection and drug resistance · 2026
    Article
  7. Review
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bing HeDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, 130021, China.
Xuewen LiDepartment of Hematology, First Hospital of Jilin University, Changchun, 130021, China.
Rongrong DongDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, 130021, China.
Han YaoDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, 130021, China.
Qi ZhouDepartment of Pediatrics, First Hospital of Jilin University, Changchun, 130021, China.
Changyan XuMedical Department, First Hospital of Jilin University, Changchun, 130021, China.
Chengming ShangInformation center, First Hospital of Jilin University, Changchun, 130021, China.
Bo ZhaoDepartment of Laboratory Medicine, Meihekou Central Hospital, Meihekou, 135000, China.
Huiling ZhouDepartment of Laboratory Medicine, Meihekou Central Hospital, Meihekou, 135000, China.
Xinqiao YuDepartment of Laboratory Medicine, Meihekou Central Hospital, Meihekou, 135000, China.
Jiancheng XuDepartment of Laboratory Medicine, First Hospital of Jilin University, Changchun, 130021, China. xjc@jlu.edu.cn.ORCID http://orcid.org/0000-0001-8796-271X

Funding

Jilin Science and Technology Development Program 20220401085YY
6 · The paper itself

Abstract

Severe Mycoplasma pneumoniae pneumonia (SMPP) poses significant diagnostic challenges due to its clinical features overlapping with those of other common respiratory diseases. This study aims to develop and validate machine learning (ML) models for the early identification of SMPP and the risk prediction for liver and heart damage in SMPP using accessible laboratory indicators. Cohort 1 was divided into SMPP group and other respiratory diseases group. Cohort 2 was divided into myocardial damage, liver damage, and non-damage groups. The models built using five ML algorithms were compared to screen the best algorithm and model. Receiver Operating Characteristic (ROC) curves, accuracy, sensitivity, and other performance indicators were utilized to evaluate the performance of each model. Feature importance and Shapley Additive Explanation (SHAP) values were introduced to enhance the interpretability of models. Cohort 3 was used for external validation. In Cohort 1, the SMPP differential diagnostic model developed using the LightGBM algorithm achieved the highest performance with AUC

Indexed as

Machine LearningMycoplasma pneumoniaePneumonia, MycoplasmaAlgorithmsChildChild, PreschoolDiagnosis, DifferentialFemaleHumansInfantMaleRisk AssessmentROC CurveChildrenLightGBMMachine learningModelSevere Mycoplasma pneumoniae pneumonia

Identifiers

PMID40108182
PMCPMC11923196

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.