Evidence map›Paper›PMID 40108158›Full record

ArticleNature communications2025

Sterically chained amino acid-rich water-soluble carbon quantum dots as a robust tumor-targeted drug delivery platform.

Wenjing Xie, Haoyu Wang, Huimin Xu, Wen Su, Ting Yuan, Jianqiao Chang, Yiqi Bai, Yixiao Fan, Yang Zhang, Yunchao Li and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Aqueous/Alcohol-Soluble Carbon Dot Light-Emitting Diodes.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  3. Review
  4. Review
  5. The Protective Effect of N, Ce-doped Carbon Dots Against HApplied biochemistry and biotechnology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenjing Xie *Key Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Haoyu Wang *Key Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Huimin Xu *Key Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Wen Su *Key Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.ORCID http://orcid.org/0000-0002-5023-9445
Ting YuanKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Jianqiao ChangKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Yiqi BaiKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Yixiao FanKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Yang ZhangKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China. y.zhang@bnu.edu.cn.ORCID http://orcid.org/0000-0002-3002-4367
Yunchao LiKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.ORCID http://orcid.org/0000-0002-5554-7252
Xiaohong LiKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China.
Louzhen FanKey Laboratory of Theoretical & Computational Photochemistry and Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing, 100875, China. lzfan@bnu.edu.cn.ORCID http://orcid.org/0000-0002-1319-5412

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22172008, 21872010
6 · The paper itself

Abstract

Effective antitumor nanomedicines maximize therapeutic efficacy by prolonging drug circulation time and transporting drugs to target sites. Although numerous nanocarriers have been developed for accurate tumor targeting, their limited water solubility makes their stable storage challenging, and poses biosafety risks in clinical translation. Herein, we choose reduced glutathione (GSH) to quick synthesize gram-scale water-soluble large amino acids mimicking carbon quantum dots (LAAM GSH-CQDs) enriched in steric chain amino acid groups with solubility of up to 2.0 g mL

Indexed as

Amino AcidsCarbonDrug Delivery SystemsNeoplasmsQuantum DotsAnimalsAntineoplastic AgentsCell Line, TumorDoxorubicinDrug CarriersFemaleGlutathioneHumansMiceMice, Inbred BALB CSolubilityAmino AcidsAntineoplastic AgentsCarbonDoxorubicinDrug CarriersGlutathioneWater

Identifiers

PMID40108158
PMCPMC11923112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.