Evidence map›Paper›PMID 40108101›Full record

ArticleDigestive diseases and sciences2025

Older Adults with Inflammatory Bowel Disease Epidemiology in the United States: 2000-2021.

Pojsakorn Danpanichkul, Yanfang Pang, Chawinthorn Vuthithammee, Disatorn Dejvajara, Priyata Dutta, Passisd Laoveeravat, Omar Al Ta'ani, Agnes Hy Ho, Chun Wei Pan, Nicole Shu Ying Tang and 7 more

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Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Pojsakorn Danpanichkul *Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, USA. pojsakorndan@gmail.com.
Yanfang Pang *Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China.
Chawinthorn VuthithammeeDepartment of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Disatorn DejvajaraFaculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Priyata DuttaDepartment of Internal Medicine, Trinity Health Ann Arbor Hospital, Ypsilanti, MI, USA.
Passisd LaoveeravatDivision of Digestive Diseases and Nutrition, University of Kentucky College of Medicine, Lexington, KY, USA.
Omar Al Ta'aniAllegheny Health Network, Pittsburgh, PA, USA.
Agnes Hy HoDepartment of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Chun Wei PanDepartment of Medicine, John H. Stroger Jr Hospital of Cook County, Chicago, IL, USA.
Nicole Shu Ying TangDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kanokphong SuparanDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Rashid N LuiDepartment of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Donghee KimDivision of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA.
Siew C NgDepartment of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Gursimran Singh KochharDivision of Gastroenterology, Hepatology & Nutrition, Allegheny Health Network, Pittsburgh, PA, USA.
Francis A Farraye *Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
Karn Wijarnpreecha *Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the United States population ages, the incidence and prevalence of inflammatory bowel disease (IBD) among older adults are on the rise.

aimsThis study provides updated estimates of the IBD burden in older adults and examines changes from 2000 to 2021.

methodsWe analyzed data on IBD incidence, prevalence, and disability-adjusted life years (DALYs) in older adults (> 70 years) in the United States from the Global Burden of Disease Study 2021, stratified by sex and state. Using the Joinpoint regression model, we evaluated age-standardized rate changes from 2000 to 2021.

resultsThe study estimated 11,250 new cases, 180,880 prevalent cases, and 80,410 DALYs from IBD in older adults in the United States in 2021. In 2021, older adults-onset represented 15% of the total IBD population in the United States, a 3% increase since 2000. Between 2000 and 2021, the incidence (Annual percent change [APC]: 0.58%, 95%CI 0.50 to 0.66%) and DALYs rates (APC: 0.34%, 95%CI 0.07 to 0.62%) increased, while the prevalence rates remained stable. Incidence rate increased at a higher extent in older adults-onset IBD in females compared to that of males. Forty-seven states experienced increased older adults-onset IBD incidence rates during this period.

conclusionFrom 2000 to 2021, the incidence and disability rates of older adults-onset IBD increased in the United States. Although older males initially had higher incidence rates, the rates have disproportionately increased among older females. The proportion of older adults-onset IBD cases and related disability has also grown, highlighting the urgent need for strategies to address the rising IBD burden in older adults.

Indexed as

Inflammatory Bowel DiseasesAgedAged, 80 and overDisability-Adjusted Life YearsFemaleHumansIncidenceMalePrevalenceUnited StatesCrohn’s diseaseDisparityGeriatricsInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID40108101

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.