ArticleBioresources and bioprocessing2025
Efficient downstream processing of second-generation lactic acid from lignocellulosic waste using aqueous two-phase extraction.
Article in Bioresources and bioprocessing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Research Progress in the Production of D-Lactic Acid from Renewable Resources.Foods (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The utilization of low-cost, waste-derived lignocellulosic biomass for biotechnological lactic acid production is an area of significant interest. Although numerous attempts have been made to develop novel processes using second-generation feedstocks, the downstream recovery processes for second-generation lactic acid are still relatively uncharted. In this context, this study explores a two-step method for retrieving second-generation lactic acid from a fermented olive leaves medium. The initial step involves an aqueous two-phase extraction using an ethanol/ammonium sulfate system, a method first applied here to lactic acid derived from second-generation raw materials. This is followed by a purification step using activated carbon. The process succeeded in extracting second-generation lactic acid with a yield of 70.02 ± 2.29% in the first extraction stage, followed by a yield of 88.91 ± 0.49% in the second purification step. The lactic acid purity level at the end of the downstream process was 90.17 ± 1.55%, as confirmed by the HPLC data. Furthermore, the study examined the feasibility of direct lactic acid extraction from unfiltered, fermented olive leaves medium, revealing that up to 95.23 ± 0.42% of bacterial cells could be eliminated. The purified lactic acid underwent qualitative identification through FT-IR and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.