Evidence map›Paper›PMID 40107990›Full record

ArticleEuropean journal of ageing2025

The association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries.

Lee Smith, Guillermo F López Sánchez, Jae Il Shin, Hans Oh, Karel Kostev, Mark A Tully, Yvonne Barnett, Laurie T Butler, Nicola Veronese, Pinar Soysal and 2 more

Abstract read
In one paragraph

Article in European journal of ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lee SmithCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Guillermo F López SánchezDivision of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain. gfls@um.es.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea. shinji@yuhs.ac.
Hans OhSuzanne Dworak Peck School of Social Work, University of Southern California, Los Angeles, CA, USA.
Karel KostevUniversity Clinic of Marburg, Marburg, Germany.
Mark A TullySchool of Medicine, Ulster University, Londonderry, Northern Ireland, UK.
Yvonne BarnettCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Laurie T ButlerCentre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK.
Nicola VeroneseSaint Camillus International University of Health Sciences, Faculty of Medicine, Rome, Italy.
Pinar SoysalDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Louis JacobResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain.
Ai KoyanagiResearch and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain.

Funding

European Union Next Generation EU
6 · The paper itself

Abstract

Studies from high-income countries have shown that multimorbidity is associated with increased fall risk among older adults. However, studies specifically on this topic from low- and middle-income counties (LMICs) are lacking. Thus, we aimed to assess this association among adults aged ≥ 50 years from six LMICs.Cross-sectional, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analyzed. Eleven chronic physical conditions were assessed. The presence of past 12-month fall-related injury was ascertained through self-reported information. Multivariable logistic regression and mediation analysis was conducted to assess the association between multimorbidity and fall-related injury.Data on 34,129 adults aged ≥ 50 years [mean (SD) age 62.4 (16.0) years; males 48.0%] were analyzed. Overall, compared to having no chronic conditions, having 2, 3, and ≥ 4 chronic conditions were significantly associated with 1.67 (95%CI = 1.21-2.30), 2.64 (95%CI = 1.89-3.68), and 3.67 (95%CI = 2.42-5.57) times higher odds for fall-related injury. The association between multimorbidity (i.e., ≥ 2 chronic conditions) and fall-related injury was mainly explained by pain/discomfort (mediated% 39.7%), mobility (34.1%), sleep/energy (24.2%), and cognition (13.0%).Older adults with multimorbidity in LMICs are at increased odds for fall-related injury. Targeting the identified potential mediators among those with multimorbidity may reduce fall risk in this population.

Indexed as

Chronic diseaseEpidemiologyFallsLow-and middle-income countriesMultimorbidity

Identifiers

PMID40107990
PMCPMC11923311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.