ArticleBMJ case reports2025
Distal femoral bone defect treatment using an engineered hydroxyapatite cylinder scaffold made from rattan wood.
Article in BMJ case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Laser-Enhanced Biomorphic Scaffolds Support Multipotent Stem Cell Differentiation and Angiogenesis for Vascularised Bone Regeneration.Journal of functional biomaterials · 2026Article
- Plant-Derived Bone Substitute Presents Effective Osteointegration in Several Clinical Settings: A Pilot Study from a Single Center.Bioengineering (Basel, Switzerland) · 2025Article
- Biomimetic Three-Dimensional (3D) Scaffolds from Sustainable Biomaterials: Innovative Green Medicine Approach to Bone Regeneration.Journal of functional biomaterials · 2025Review
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Distal femoral non-union presents significant challenges, often requiring complex treatment strategies to achieve bone healing. In this case, a young male patient with an open fracture of the distal femur developed an atrophic non-union, 9 months after initial fixation. The patient underwent surgical intervention with debridement, leading to a 2.2 cm bone defect and placement of a cylindrical synthetic bone graft (b.Bone), combined with bone marrow aspirate concentrate. This approach aimed to provide structural support and enhance biological healing. The choice of the cylindrical graft was due to its optimal fit and support for the anterior femoral cortex. Postoperative outcomes were favourable, with successful bone healing, confirmed radiologically, and restoration of function. This case demonstrates the potential of synthetic bone substitutes augmented with biological agents as a promising alternative to traditional grafts in managing complex non-unions.
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Registered trials
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