Evidence map›Paper›PMID 40107719›Full record

Trial reporteNeuro2025

Clinical Efficacy of Atomoxetine Hydrochloride Combined with Electroencephalogram Biofeedback in Attention-Deficit/Hyperactivity Disorder in Children.

Xinyue Liu, Xiaoliang Li, Limin Liu, Xiao Sun, Zhe Yu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinyue LiuDepartment of Paediatrics, Xingtai Central Hospital, Xingtai, Hebei 054000, China.
Xiaoliang LiDepartment of Paediatrics, Xingtai Central Hospital, Xingtai, Hebei 054000, China Lixiaoliang2231@163.com.ORCID https://orcid.org/0009-0007-3855-3005
Limin LiuDepartment of Paediatrics, Xingtai Central Hospital, Xingtai, Hebei 054000, China.
Xiao SunDepartment of Paediatrics, Xingtai Central Hospital, Xingtai, Hebei 054000, China.
Zhe YuDepartment of Paediatrics, Xingtai Central Hospital, Xingtai, Hebei 054000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) adversely affects the learning, social interaction, and daily living of affected children. Atomoxetine (ATX) hydrochloride (HCI) has been widely used in clinical practice. Electroencephalogram (EEG) biofeedback, as a nonpharmacological treatment approach, has also demonstrated potential in improving symptoms in children with ADHD. We aimed to investigate the clinical efficacy of combining ATX HCI with EEG biofeedback in the treatment of ADHD in children. We hypothesized that this combined therapy would be more effective in alleviating symptoms in children with ADHD. Ninety children with ADHD were randomly separated into the control group (receiving ATX HCI treatment for 12 weeks) and study group (receiving ATX HCI treatment for 12 weeks combined with 60 sessions of EEG biofeedback treatment;

Indexed as

Adrenergic Uptake InhibitorsAtomoxetine HydrochlorideAttention Deficit Disorder with HyperactivityBiofeedback, PsychologyElectroencephalographyAdolescentChildCombined Modality TherapyFemaleHumansMaleTreatment OutcomeAdrenergic Uptake InhibitorsAtomoxetine Hydrochlorideatomoxetine hydrochlorideattentionattention-deficit/hyperactivity disorderchildrenclinical efficacycontrol abilityelectroencephalogram biofeedback

Identifiers

PMID40107719
PMCPMC11967376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.