Evidence map›Paper›PMID 40107692›Full record

ArticleBMJ open2025

Evaluation of how US women react to a decision aid informing them of the harms and benefits of mammography: a qualitative study.

Brad Morse, Tamar Parmet, Grant Yoder, Channing E Tate, Carmen L Lewis, Kirsten McCaffery, Joseph N Cappella, Jolyn Hersch, Marilyn M Schapira, Laura D Scherer

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05376241 (Understanding Affective Processing of Scientific Evidence to Promote Informed Choice for Breast Cancer Screening), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05376241 phase2completednot on this map

Understanding Affective Processing of Scientific Evidence to Promote Informed Choice for Breast Cancer Screening

TypeinterventionalSponsorUniversity of Colorado, DenverRan2022 to 2022Enrolled637ConditionsBreast CancerArmsDecision aid
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brad MorseUniversity of Colorado School of Medicine, Aurora, Colorado, USA brad.morse@cuanschutz.edu.ORCID http://orcid.org/0000-0002-1080-3961
Tamar ParmetUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Grant YoderUniversity of Colorado School of Medicine, Aurora, Colorado, USA.
Channing E TateUniversity of Colorado School of Medicine, Aurora, Colorado, USA.ORCID http://orcid.org/0000-0001-6635-9794
Carmen L LewisUniversity of Colorado Denver, Denver, Colorado, USA.ORCID http://orcid.org/0000-0002-9739-2850
Kirsten McCafferySydney Health Literacy Lab, School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-2696-5006
Joseph N CappellaUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jolyn HerschSchool of Public Health, University of Sydney, The University of Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0001-5225-6639
Marilyn M SchapiraUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Laura D SchererUniversity of Colorado Denver School of Medicine, Aurora, Colorado, USA.

Funding

Understanding affective processing of scientific evidence to promote informed choice for breast cancer screeningR37CA254926 · NCI · UNIVERSITY OF COLORADO DENVER · PI Laura D. Scherer · 2021 to 2026
$3.8M
NCI NIH HHS R37 CA254926
6 · The paper itself

Abstract

objectivesTo evaluate how women react to a decision aid (DA) informing them of the harms and benefits of mammography, including overdiagnosis.

backgroundBreast cancer is the most common cancer affecting women. In efforts to reduce mortality, mammography has been widely accepted as an effective method of early detection. However, there is a balance between the known harms and benefits of breast cancer screening. Overdiagnosis is the detection of a cancer that would never cause harm over the lifetime. Comprehension and acceptance of overdiagnosis can be difficult for some people.

designQualitative study using a semistructured interview protocol. Data were analysed in Atlas.Ti and the framework method was used to identify themes.

settingTelephone interviews with participants living in the USA.

participants30 female individuals aged 39-49, selected from a nationally representative US sample of individuals who had completed a survey <2 weeks prior, during which they viewed a DA describing the main harms and benefits of breast cancer screening.

resultsSix major themes were identified: (1) overdiagnosis and false positives were often conflated, (2) previous experience and the influence of doctors and family supersedes new information, (3) beliefs about cancer dominate acceptance and comprehension of overdiagnosis, (4) emotional reactions to the novelty of overdiagnosis, (5) reactions to screening benefits-"I'll be the one", and (6) people reported the DA is credible, but they remained sceptical and performed their own research.

conclusionThis study provides insights into the challenges of communicating about the harms of breast cancer screening, particularly overdiagnosis. While it is critical to honestly communicate with patients about the harms of breast cancer screening, it is also important to consider the emotional impact of conveying such information.

Indexed as

Breast NeoplasmsDecision Support TechniquesEarly Detection of CancerMammographyOverdiagnosisAdultFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMiddle AgedQualitative ResearchUnited StatesBreast imagingDecision MakingONCOLOGYQUALITATIVE RESEARCH

Identifiers

PMID40107692
PMCPMC11927412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.