Evidence map›Paper›PMID 40107662›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2025

Interplay between respiratory viruses and cilia in the airways.

Katie Horton, Peter A C Wing, Claire L Jackson, Christopher J McCormick, Mary P Carroll, Jane S Lucas

Abstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Mucins and Respiratory Virus Infection.Annual review of virology · 2026
    Review
  3. Observational
  4. Article
  5. Article
  6. Goblet cells dictate viral tropism and pathogenesis in nasal and intestinal mucosae.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katie HortonSchool of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, UK.ORCID https://orcid.org/0000-0002-9357-928X
Peter A C WingChinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK.
Claire L JacksonSchool of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, UK.
Christopher J McCormickSchool of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, UK.
Mary P CarrollPrimary Ciliary Dyskinesia Centre, NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Jane S LucasSchool of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton, UK jlucas1@soton.ac.uk.ORCID https://orcid.org/0000-0001-8701-9975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The airway epithelium is the first point of contact for inhaled pathogens. The role of epithelial cells in clearance, infection and colonisation of bacteria is established. The interactions of respiratory viruses and cilia is less understood, but viruses are known to target ciliated epithelial cells for entry, replication and dissemination. Furthermore, some respiratory viruses impair and/or enhance ciliary activity. This review examines what is known about the interactions between cilia and viral infection and how respiratory viruses effect cilia function with subsequent consequences for human health. We discuss the models which can be used to investigate the relationship between respiratory viruses and the host airway.

Indexed as

CiliaRespiratory MucosaRespiratory Tract InfectionsVirus DiseasesVirusesAnimalsEpithelial CellsHost-Pathogen InteractionsHumans

Identifiers

PMID40107662
PMCPMC11920889

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.