Evidence map›Paper›PMID 40107593›Full record

ReviewThe Annals of thoracic surgery2025

Indications and Practical Considerations for Partial Heart Transplantation.

Taufiek Konrad Rajab, David M Kalfa, Carlos M Mery, Sitaram M Emani, Brian L Reemtsen

Abstract readReview
In one paragraph

Review in The Annals of thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taufiek Konrad RajabDivision of Cardiovascular Surgery, Department of Surgery, Arkansas Children's Hospital, Little Rock, Arkansas. Electronic address: tkrajab@uams.edu.
David M KalfaSection of Pediatric and Congenital Cardiac Surgery, Division of Cardiac, Thoracic, and Vascular Surgery, Department of Surgery, Morgan Stanley Children's Hospital, New York, New York.
Carlos M MeryDivision of Pediatric Cardiac Surgery, Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Sitaram M EmaniDepartment of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts.
Brian L ReemtsenDivision of Cardiovascular Surgery, Department of Surgery, Arkansas Children's Hospital, Little Rock, Arkansas.

Funding

An expandable polymeric valved conduit to repair congenital heart diseaseR01HL155381 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FERRARI, GIOVANNI · 2021 to 2025
$2.8M
Ex Vivo Storage, Preservation And Rehabilitation Of Living Heart Valves For Allogenic Valve TransplantationR01HL179224 · NHLBI · FLORIDA INTERNATIONAL UNIVERSITY · PI David Kalfa · 2025 to 2026
$1.4M
Evaluation of growth potential of ice-free vitrified heart valves in a pediatric porcine model.R41HL169059 · NHLBI · TISSUE TESTING TECHNOLOGIES, LLC · PI RAJAB, TAUFIEK KONRAD · 2023 to 2023
$611k
NHLBI NIH HHS R01 HL155381NHLBI NIH HHS R01 HL179224NHLBI NIH HHS R41 HL169059
6 · The paper itself

Abstract

Partial heart transplantation is a new approach to deliver growing heart valve substitutes for children. The rationale for partial heart transplantation is that the valves contained in heart transplants grow. Partial heart transplants differ from heart transplants because only the part of the heart containing the necessary valve is transplanted, while the native ventricles are preserved. Preserving the native ventricles eliminates the risk of graft ventricular dysfunction and allows for utilization of donor hearts with ventricular dysfunction. Here we outline practical considerations for partial heart transplantation, including indications, sources for donor hearts, graft procurement, graft preservation, implantation, recipient immunosuppression, and reimbursement. This invited expert review is intended to help clinical teams implement partial heart transplantation.

Indexed as

Heart TransplantationChildHumans

Identifiers

PMID40107593
PMCPMC12353684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.