Observational studyAmerican journal of infection control2025
Changing trends in the sources and volumes of clinical cultures with Candida auris at an integrated health system in Miami, Florida, United States, 2019-2023.
Observational study in American journal of infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Multicenter performance evaluation of the SimplexaJournal of clinical microbiology · 2026Article
- Stable bloodstream infection rates despite rising colonization: insights from a hospital system using in-house polymerase chain reaction screening forAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Candidiasis epidemiology and outcomes including emergence ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundCandida auris (C auris) has rapidly spread in the United States. We aimed to characterize the trends in volumes and sources of clinical cultures with C auris at a large health care system.
methodsWe conducted a retrospective observational study including clinical cultures with C auris collected between April 1, 2019, and December 31, 2023. Surveillance cultures were excluded. Clinical specimens were processed through routine methods, and identification was performed using mass spectrometry. Whole-genome sequencing was performed on select specimens.
resultsWe identified 327 clinical cultures belonging to 231 unique patients. The number of clinical cultures increased each year, from 5 in 2019 to 29 in 2020 (580%), 71 in 2021 (251% relative to 2020), 107 in 2022 (46% relative to 2021), and 115 in 2023 (7% relative to 2022). Blood cultures were the most common source, but specimens originating from soft tissue/bone infections had a large increase in 2022 and 2023. All sequenced isolates belong to clade III (South African clade) and were resistant to fluconazole and susceptible to echinocandins and amphotericin B.
conclusionsThe volumes of clinical cultures with C auris have rapidly increased, accompanied by an expansion in the sources of infection.
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