Evidence map›Paper›PMID 40107292›Full record

ArticleArquivos de neuro-psiquiatria2025

Dysphagia and its impact on quality of life in rare neuromuscular disorders.

Déborah Santos Sales, Mariana Beiral Hammerle, Vívian Pinto de Almeida, Clarissa de Araujo Davico, Patricia Gomes Pinheiro, Rayanne da Silva Souza, Stephanie de Freitas Canelhas, Marcele Silva Carvalho, Karina Lebeis Peres

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Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Déborah Santos SalesUniversidade Federal do Estado do Rio de Janeiro, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-8619-2925
Mariana Beiral HammerleUniversidade Federal do Estado do Rio de Janeiro, Hospital Universitário Gaffrée e Guinle, Rio de Janeiro RJ, Brazil.ORCID 0000-0001-6956-1795
Vívian Pinto de AlmeidaUniversidade Federal do Estado do Rio de Janeiro, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-1447-0009
Clarissa de Araujo DavicoCasa Hunter, São Paulo SP, Brazil.ORCID 0000-0003-0337-166X
Patricia Gomes PinheiroUniversidade Federal do Estado do Rio de Janeiro, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-1044-7530
Rayanne da Silva SouzaCasa Hunter, São Paulo SP, Brazil.ORCID 0000-0001-8640-066X
Stephanie de Freitas CanelhasCasa Hunter, São Paulo SP, Brazil.ORCID 0000-0002-9635-9813
Marcele Silva CarvalhoUniversidade Veiga de Almeida, Rio de Janeiro RJ, Brazil.ORCID 0009-0002-1393-0760
Karina Lebeis PeresUniversidade Federal do Estado do Rio de Janeiro, Rio de Janeiro RJ, Brazil.ORCID 0000-0002-9114-4514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with neuromuscular diseases (NMDs) often face swallowing difficulties (dysphagia) as part of their condition.

objectiveTo determine the prevalence of self-reported swallowing disorders in patients with rare NMDs and examine their correlation with related quality of life (QoL).

methodsThe study included 103 patients with confirmed rare NMDs. Dysphagia risk was assessed using the validated Eating Assessment Tool-10 (EAT-10), and QoL related to swallowing was measured with the SWAL-QoL survey. Correlations between EAT-10 and SWAL-QoL scores were analyzed. Additionally, the mean questionnaire scores were compared among patients classified as dysphagic, dysphagic with high aspiration risk, and nondysphagic.

resultsThe estimated prevalence of dysphagia in the cohort, based on EAT-10, was 52.4%. Higher scores were significantly correlated with poorer swallowing-related QoL, except for the sleep domain. The most affected SWAL-QoL domains were burden, eating desire, eating duration, food selection, communication, fear, mental health, social functioning, and dysphagia battery score (DBS), with significant differences observed among the classifications (

conclusionDysphagia is a prevalent symptom in patients with rare NMDs, affecting 52.4% of the cohort and significantly impacting QoL in nearly all domains except sleep.

Indexed as

Deglutition DisordersNeuromuscular DiseasesQuality of LifeRare DiseasesAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceSelf ReportSurveys and QuestionnairesYoung Adult

Identifiers

PMID40107292
PMCPMC11922619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.