ArticleArquivos de neuro-psiquiatria2025
Aerobic physical exercise improves quality of life in temporal lobe epilepsy.
Article in Arquivos de neuro-psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Temporal lobe epilepsy and its negative impact on quality of life: could it improve through aerobic physical exercise?Arquivos de neuro-psiquiatria · 2026Article
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10 authors.
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Abstract
backgroundA prior study showed that people with temporal lobe epilepsy (TLE) with an active lifestyle present a better quality of life (QoL), but the influence of aerobic physical exercise (APE) in the QoL of these patients is still unclear. As pharmacoresistance is commonly associated with TLE, the possibility of seizures during the activities might prevent patients from benefiting from APE.
objectiveTo analyze the influence of APE in the QoL of TLE patients and also focus on the seizure worry subitem of the QoL in epilepsy 31 (QoLIE-31) questionnaire.
methodsWe analyzed data from 25 individuals with TLE who participated in a 6-month APE program under the supervision of a board-certified physical trainer. TLE patients were divided into training (TLE-training) and control (TLE-control) groups. The TLE-training group underwent an APE program of 6 months, while the control group was oriented to keep their routine. We assessed all patients with the QoLIE-31 at baseline and after 6 months. We used a mixed-between-subjects ANOVA to assess the APE intervention compared with TLE-control pre- and postintervention on the QoL.
resultsWe found a significant interaction between intervention groups and APE-time (
conclusionThere was improvement in QoL due to APE, with no increase in seizure worry, which might be a feature of concern for both patients and healthcare practitioners. Further studies should focus on long-term interventions to evaluate the impact of APE in QoL.
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