Evidence map›Paper›PMID 40106814›Full record

SynthesisJournal of medical Internet research2025

Behavioral Therapy-Based Digital Interventions for Treating Osteoarthritis: Systematic Review and Meta-Analysis.

Beiyao Zhu, Dian Zhu, Xiao'ao Xue, Hongyi Yang, Shurong Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beiyao Zhu *Shanghai Jiao Tong University, The Ninth People's Hospital, Shanghai, China.ORCID 0000-0002-6443-5586
Dian Zhu *School of Design, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-1710-6659
Xiao'ao XueDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-7478-9425
Hongyi YangSchool of Design, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0002-8293-3669
Shurong ZhangDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-2034-1219

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoarthritis (OA) is characterized by pain, functional impairments, muscle weakness, and joint stiffness. Since OA heightens reliance on heath care resources and exacerbates socioeconomic burden, remote OA rehabilitation using digital technologies is rapidly evolving.

objectiveThe aim of this study was to analyze the efficacy of behavioral therapy-based digital interventions for patients with OA.

methodsThis study is a systematic review of randomized controlled trials (RCTs) that assessed the effects of behavioral therapy-based digital intervention tools for OA. These RCTs were searched from inception to June 2023 in the Web of Science, Embase, Cochrane Library, Ovid, and PubMed databases.

resultsTen eligible RCTs comprising 1895 patients with OA were included. Digital tools based on either cognitive behavioral therapy (CBT) or behavior change technique (BCT) were investigated. All studies demonstrated low-to-moderate effects on pain reduction in the short term (standardized mean difference [SMD] -0.20, 95% CI -0.35 to -0.05). Six studies reported improvement in physical function (SMD -0.20, 95% CI -0.41 to 0.00), and 5 confirmed increased pain self-efficacy (SMD 0.22, 95% CI 0.02-0.42). In subgroup analysis, compared with CBT, BCT-based digital interventions demonstrated their effects on pain reduction (SMD -0.25, 95% CI -0.49 to 0.00) and physical function (SMD -0.26, 95% CI -0.54 to -0.01) in the short term. In addition, physiotherapist involvement in treatment had a positive effect on pain control (SMD -0.14, 95% CI -0.27 to -0.02). Furthermore, web-based digital tools improved physical function in the short term (SMD -0.28, 95% CI -0.54 to -0.01).

conclusionsModerate- and low-quality evidence supported that behavioral therapy-based digital tools improved pain intensity, physical function, and self-efficacy in the short term. However, affective interactions between patients and professionals may affect the clinical outcomes.

trial registrationPROSPERO CRD42023430716; https://tinyurl.com/yc49vzyy.

Indexed as

Behavior TherapyCognitive Behavioral TherapyOsteoarthritisHumansRandomized Controlled Trials as Topicbehavioral therapydigital interventionimpairmentmeta-analysisosteoarthritispainpain reductionpatientpsychotherapy-based digital interventionquality of lifesocioeconomic burdensystematic reviewtreatment

Identifiers

PMID40106814
PMCPMC11966084

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.