Evidence map›Paper›PMID 40106796›Full record

ArticleJournal of the American Chemical Society2025

Revision of the Formycin A and Pyrazofurin Biosynthetic Pathways Reveals Specificity for d-Glutamic Acid and a Cryptic

Ziyang Zheng, Daan Ren, Yeonjin Ko, Hung-Wen Liu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ziyang ZhengDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0009-0004-9700-4178
Daan RenDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-1309-5382
Yeonjin KoDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Hung-Wen LiuDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0001-8953-4794

Funding

Three-Membered Ring Metabolites, Inhibition &FormationR01GM040541 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI LIU, HUNG-WEN · 1989 to 2023
$7.4M
Novel Mechanisms of Catalysis in Natural Product BiosynthesisR35GM153203 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI HUNG-WEN LIU · 2024 to 2026
$2.0M
NIGMS NIH HHS R01 GM040541NIGMS NIH HHS R35 GM153203
6 · The paper itself

Abstract

Formycin A and pyrazofurin are two naturally occurring pyrazole-derived

Indexed as

FormycinsGlutamic AcidPyrazolesAcylationBiosynthetic PathwaysSubstrate SpecificityFormycinsGlutamic AcidPyrazoles

Identifiers

PMID40106796
PMCPMC11964824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.