SynthesisEuropean journal of preventive cardiology2025
Impact of neighbourhood and environmental factors on the risk of incident cardiovascular disease: a systematic review and meta-analysis.
Synthesis in European journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The relationship between noise pollution and cardiovascular diseases: an umbrella review on meta-analyses.BMC cardiovascular disorders · 2025Pooled it
- Area deprivation, social vulnerability, and post-pregnancy blood pressure.medRxiv : the preprint server for health sciences · 2026Article
- Impact of sensory impairments on the risk of mortality and hospitalisations: longitudinal insights from REGLINK-SHAREDK.BMJ public health · 2026Article
- Microbiota-Driven Immune Dysregulation Along the Gut-Lung-Vascular Axis in Asthma and Atherosclerosis.Biomedicines · 2025Review
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6 authors.
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Abstract
aimsWe aimed to study the association of five key neighbourhood exposures in large cohort studies and risk of incident cardiovascular disease (CVD). METHODS AND
resultsWe conducted a systematic search of MEDLINE, The Cochrane Library, Web of Science, and Embase from database inception to 20th October 2024. Included studies reported both incident (first-time) CVD diagnosis and neighbourhood exposures across five domains: retail environment, health services, physical environment, pollution, and neighbourhood deprivation. A random-effects meta-analysis was performed to estimate pooled risk of CVD across domains. Of 39 studies included in the systematic review, 28 qualified for meta-analysis representing over 41 million people. The most frequently examined exposures were air pollution (n = 17), followed by noise pollution (n = 9), socioeconomic (n = 6), green and blue spaces (n = 3), and health and retail environments (n = 4). Higher concentrations of particulate matter 2.5 {PM2.5; hazard ratio (HR): 1.16 [95% confidence interval (95% CI): 1.09-1.24] per 10 µg/m³ increase}, higher nitrogen dioxide [NO2; HR: 1.05 (95% CI: 1.02-1.07) per 10 ppb increase], road traffic noise [risk ratio (RR): 1.03 (95% CI: 1.02-1.05) per 10 dB increase], and high neighbourhood-level deprivation [RR: 1.24 (95% CI: 1.17-1.31) vs. low] were each associated with increased risk of incident CVD development.
conclusionOur findings indicate a modest yet significant increase in CVD risk associated with elevated levels of air pollution, road noise, and neighbourhood deprivation, emphasizing these exposures as consequential targets for policy intervention.
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