Evidence map›Paper›PMID 40106657›Full record

SynthesisCancer nursing

The Barriers and Enablers to Participation in Oncology Clinical Trials for Ethnically Diverse Communities: A Qualitative Systematic Review Using Metaethnography.

Lorraine Turner, Sally Taylor, Ashleigh Ward, Fiona Thistlethwaite, Janelle Yorke

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Faith, Culture, and Cancer: A Qualitative Study Exploring Muslim Women's Perspectives on Clinical Trials in the United Kingdom.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lorraine TurnerAuthor Affiliations: Department of Research & Innovation (Ms Turner) and Christie Patient Centred Research (Dr Taylor, Ms Ward and Professor Yorke), The Christie NHS Foundation Trust; School of Nursing, Midwifery and Social Work, The University of Manchester (Ms Turner and Professor Yorke); Department of Medical Oncology, The Christie NHS Foundation Trust (Professor Thistlethwaite); and Division of Cancer Sciences, School of Medical Sciences, The University of Manchester (Professor Thistlethwaite), Manchester, United Kingdom.ORCID 0000-0002-2487-0540
Sally Taylor
Ashleigh Ward
Fiona Thistlethwaite
Janelle Yorke

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRacial and ethnic inequities exist in cancer clinical trial participation. Low recruitment across ethnically diverse communities contributes to health inequalities further disproportionately affecting these groups. Understanding barriers and enablers to clinical trial participation for ethnic minorities is key to developing strategies to address this problem.

objectiveTo explore, evaluate, and synthesize qualitative research surrounding patients' lived experiences and perceptions of participating in cancer clinical trials from ethnically diverse groups.

methodsNoblit and Hare's 7-stage metaethnography was used. Seven databases were searched. Inclusion criteria were as follows: qualitative studies published in English from January 1, 2012, to January 31, 2022; patients from any ethnic minority 18 years and older with a cancer diagnosis; and cancer patients' carers and healthcare professionals (HCPs)/healthcare leaders involved in the delivery of cancer clinical trials.

resultsThe majority of included articles were conducted in the United States. Interpretive qualitative synthesis resulted in 7 categories including patient perceptions and beliefs and HCP perception of trial burden and social determinants of health. Four lines of argument were established.

conclusionsThe findings capture the experience and perceptions of ethnic minority patients, their carers, HCPs, and healthcare leaders in this area of research. Incongruities exist between patient-reported barriers and those perceived by HCPs. Published empirical research outside the United States is limited. IMPLICATIONS FOR PRACTICE: When developing strategies to increase clinical trial participation, research literacy, cultural safety, and unconscious biases within healthcare need to be addressed. Further research to examine intersectionality and the role of faith in decision-making among ethnic groups is warranted.

Indexed as

Clinical Trials as TopicEthnicityNeoplasmsPatient ParticipationPatient SelectionAnthropology, CulturalFemaleHumansMaleMinority GroupsQualitative ResearchCancerClinical trialEthnicityInequalitiesParticipationQualitativeRaceResearchUnderrepresentation

Identifiers

PMID40106657
PMCPMC12871412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.