ArticleScience advances2025
Wetting-induced interfacial instability: A mechanism for droplet emission at air-liquid interfaces.
Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Autonomous and Communicative Microcapsule Systems for Life-Like Homeostatic pH Regulation.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Programmable Microcarriers for Stem Cell Therapy: Advanced Fabrication Strategies, Stem Cell Fate Regulatory Function and Biomedical Applications.International journal of molecular sciences · 2026Review
- Droplet microfluidics for biomedical applications: emerging trends and future developments.Microsystems & nanoengineering · 2026Review
- Passive Droplet Generation in T-Junction Microchannel: Experiments and Lattice Boltzmann Simulations.Micromachines · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-throughput production of monodisperse microdroplets has revolutionized many fields, typically relying on shear-induced emulsification in intricate microfluidic channels to induce the Rayleigh-Plateau instability. This mechanism exhibits low robustness due to its high dependence on the physical properties and flow conditions of fluids. Here, we report a robust emulsification mechanism-wetting-induced interfacial instability-for droplet emission. We find that, when pendant microdroplets in the air contact with an immiscible wetting bulk phase, it triggers interfacial instability in the hanging droplets and then their rapid breakup into the bulk phase. This simplifies the monodisperse microdroplet production using a nozzle positioned above an air-liquid interface, requiring no complex microchannels. We demonstrate that this method exhibits highly scalable production and exceptional robustness against variations in physical properties and flow conditions of fluids, including highly viscous non-Newtonian fluid (56,600 millipascal-seconds). This mechanism provides a simpler alternative to the traditional Rayleigh-Plateau instability for emulsification, offering opportunities for industrial applications and insights into microscale interfacial science.
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Registered trials
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