Evidence map›Paper›PMID 40106270›Full record

ArticleThe Plant journal : for cell and molecular biology2025

ABA importers ABCG17 and ABCG18 redundantly regulate seed size in Arabidopsis.

Yuqin Zhang, Moran Anfang, James H Rowe, Annalisa Rizza, Zhuorong Li, Ning Su, Hamutal Bar, Laurence Charrier, Markus Geisler, Alexander M Jones and 1 more

Abstract read
In one paragraph

Article in The Plant journal : for cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Adaptation of seed dormancy to maternal climate occurs via intergenerational transport of abscisic acid.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuqin ZhangSchool of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, 69978, Israel.ORCID 0000-0002-4872-0889
Moran AnfangSchool of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, 69978, Israel.
James H RoweSainsbury Laboratory, University of Cambridge, Cambridge, CB2 1LR, UK.
Annalisa RizzaSainsbury Laboratory, University of Cambridge, Cambridge, CB2 1LR, UK.
Zhuorong LiCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 100101, China.
Ning SuCollege of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing, 100101, China.
Hamutal BarSchool of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, 69978, Israel.
Laurence CharrierDepartment of Biology, University of Fribourg, Fribourg, CH-1700, Switzerland.
Markus GeislerDepartment of Biology, University of Fribourg, Fribourg, CH-1700, Switzerland.
Alexander M JonesSainsbury Laboratory, University of Cambridge, Cambridge, CB2 1LR, UK.ORCID 0000-0002-3662-2915
Eilon ShaniSchool of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, 69978, Israel.ORCID 0000-0002-3111-4647

Funding

European Research Council 101113412European Research Council 101118769European Research Council 757683Gatsby Charitable FoundationIsrael Science Foundation 2378/19Israel Science Foundation 3419/20Swiss National Science Foundation 165877the BR funds of Chinese Academy of Sciences 118900M089the European Research Council 101118769-HYDROSENSIthe European Research Council 757683-RobustHormoneTransthe Human Frontier Science Program HFSP-LIY000540/2020the Swiss National Funds project 310030_197563the Swiss National Funds project 31003A_165877UK Biotechnology and Biological Sciences Research Council BB/P018572/1
6 · The paper itself

Abstract

The stress hormone abscisic acid (ABA) plays a crucial role in mediating plant responses to the environment and regulating plant development. In this study, we demonstrate that two ABA importers, ABCG17 and ABCG18, control seed size by regulating the ABA levels transported into the embryo. Double knockdown of ABCG17 and ABCG18 resulted in lower ABA accumulation in the embryo, wider siliques, and increased overall seed size. Leaf phloem-specific ABA induction in the aba2-1 background showed that ABA could move from the vasculature to control seed size. ABCG17 and ABCG18 are expressed in leaves, and the reproductive organs septum, and valves but not in the developing seeds, suggesting that ABCG17 and ABCG18 affect seed size maternally. Together, the results shed light on the molecular mechanisms by which ABA is transported to the embryo to determine seed size.

Indexed as

Abscisic AcidArabidopsisArabidopsis ProteinsATP-Binding Cassette TransportersPlant Growth RegulatorsSeedsBiological TransportGene Expression Regulation, PlantPlant LeavesAbscisic AcidArabidopsis ProteinsATP-Binding Cassette TransportersPlant Growth RegulatorsABA reporterABCG proteinsAbscisic acidlong‐distance transportmaternal effectplant hormonesSeed size

Identifiers

PMID40106270
PMCPMC7617562

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.