Evidence map›Paper›PMID 40106225›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2025

Predictors of Composite Maternal and Fetal Outcomes among Pregnant Women with Early-Onset Type 2 Diabetes: A Cross-Sectional Study.

Aleksandra Z Jotic, Milica M Stoiljkovic, Tanja J Milicic, Katarina S Lalic, Ljiljana Z Lukic, Marija V Macesic, Jelena N Stanarcic Gajovic, Mina M Milovancevic, Marko H Obradovic, Miroslava G Gojnic and 2 more

Abstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aleksandra Z JoticClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia. aleksandra.z.jotic@gmail.com.
Milica M StoiljkovicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Tanja J MilicicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Katarina S LalicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Ljiljana Z LukicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Marija V MacesicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Jelena N Stanarcic GajovicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Mina M MilovancevicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Marko H ObradovicFaculty of Mathematics, University of Belgrade, Studentski Trg 16, Belgrade, Serbia.
Miroslava G GojnicFaculty of Medicine, University of Belgrade, Dr Subotica 8, 11000, Belgrade, Serbia.
Djurdja P RafailovicClinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Dr Subotica 13, 11000, Belgrade, Serbia.
Nebojsa M LalicDepartment of Medical Sciences, Serbian Academy of Sciences and Arts, Kneza Mihaila 35, 11000, Belgrade, Serbia.

Funding

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja 451-03-66/2024-03/200110
6 · The paper itself

Abstract

introductionThe most common form of pregestational diabetes in pregnancy is type 2 diabetes, requiring strict metabolic monitoring owing to the risk of adverse pregnancy outcomes. Our study aimed to identify predictors of composite maternal outcome (CMO) and fetal outcome (CFO) separately in pregnant women with early-onset type 2 diabetes (PwEOT2D).

methodsThe cross-sectional pilot study included 60 PwEOT2D by recording age, socioeconomic determinants, preconception body mass index (pBMI), preconception (pHbA1c) and trimester-specific glycated hemoglobin (HbA1c), gestational weight gain (GWG), and pregnancy outcomes. We defined CMO as at least one of the following: gestational hypertension, preeclampsia, eclampsia, preterm delivery, or emergency section. CFO included at least one of the following: small or large for gestational age, macrosomia, neonatal hypoglycemia, or admission to the neonatal intensive care unit.

resultsCMO was detected in 55% and CFO in 35% of PwEOT2D. The majority of PwEOT2D with CMO lived in suburban areas (73.1%), while those without CMO mostly lived in rural areas (51.9%, p = 0.014). Moreover, PwEOT2D with CMO had comparable pBMI to those without CMO (31.45 ± 6.27 versus 28.99 ± 6.28 kg/m

conclusionsOur results imply that preconception and first trimester of pregnancy HbA

Indexed as

Composite maternalEarly-onset type 2 diabetesFetal outcomePregnancy

Identifiers

PMID40106225
PMCPMC12006619

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.