Evidence map›Paper›PMID 40106200›Full record

ReviewDiscover oncology2025

Decoding male breast cancer: epidemiological insights, cutting-edge treatments, and future perspectives.

Lei Zhao, Huijuan Cheng, Dongqiang He, Yalan Zhang, Yahui Chai, Ailin Song, Guodong Sun

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Hotspots and future trends of male breast cancer: a global perspective.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lei Zhao *Gansu Province Key Laboratory of Environmental Oncology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China.
Huijuan Cheng *Gansu Province Key Laboratory of Environmental Oncology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China. chenghjmph@126.com.
Dongqiang HeGansu Province Key Laboratory of Environmental Oncology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China.
Yalan ZhangGansu Province Key Laboratory of Environmental Oncology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China.
Yahui ChaiDepartment of General Surgery, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Ailin SongDepartment of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China. songail@lzu.edu.cn.
Guodong SunGansu Province Key Laboratory of Environmental Oncology, The Second Hospital of Lanzhou University, Lanzhou, Gansu, China. sungd2023@lzu.edu.cn.

Funding

the Cuiying Technology Innovation Project of Lanzhou University Second Hospital CY2023-MS-B16the Gansu Province Natural Science Foundation Project 22JR5RA916the Lanzhou University First Hospital In-House Fund ldyyyn2020-46
6 · The paper itself

Abstract

Breast cancer is predominantly recognized as a condition affecting women, however, male breast cancer (MBC), despite its rarity, represents a significant and serious malignancy in men. Accounting for approximately 1% of all breast cancer cases, MBC is often diagnosed at a later stage compared to female breast cancer, primarily due to a lack of awareness and the absence of screening programs tailored for men. This delayed diagnosis typically results in poorer prognoses and more limited treatment options. Over the past decade, there has been a notable increase in research and awareness surrounding MBC. This surge is largely driven by the recognition of its unique epidemiological and biological characteristics, which are distinct from those of female breast cancer. However, due to its low incidence, many aspects of MBC, including its etiology, clinical presentation, and optimal treatment strategies, remain inadequately understood. This paper aims to provide a comprehensive review of MBC by examining its incidence, mortality rates, and epidemiological characteristics on a global scale. Additionally, it explores the economic burden associated with the disease, identifies key risk factors, and discusses current preventive measures. Finally, the paper will offer insights into future research directions and potential advancements in the diagnosis and treatment of MBC.

Indexed as

Breast neoplasmsDisease burdenEpidemiologyMaleRisk factorsTreatments

Identifiers

PMID40106200
PMCPMC11923333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.