Evidence map›Paper›PMID 40106069›Full record

ArticleClinical oral investigations2025

Effectiveness and safety of three NiTi systems in endodontic retreatment of MB1 and MB2 root canals: a micro-CT and CBCT combined analysis.

Airton Oliveira Santos-Junior, Rocharles Cavalcante Fontenele, Karina Ines Medina Carita Tavares, Fernanda Ferrari Esteves Torres, Jáder Camilo Pinto, Pedro Luis Busto Rosim, Andréa Gonçalves, Marco Antonio Hungaro Duarte, Juliane Maria Guerreiro-Tanomaru, Mário Tanomaru-Filho

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Airton Oliveira Santos-JuniorDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-1916-1675
Rocharles Cavalcante FonteneleOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-6426-9768
Karina Ines Medina Carita TavaresDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-7916-7900
Fernanda Ferrari Esteves TorresDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0631-3249
Jáder Camilo PintoDepartment of Dentistry, Centro Universitário Presidente Antônio Carlos (UNIPAC), Barbacena, Minas Gerais, Brazil.ORCID http://orcid.org/0000-0003-2023-1589
Pedro Luis Busto RosimDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0009-0009-2194-7475
Andréa GonçalvesDepartment of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8498-8199
Marco Antonio Hungaro DuarteDepartment of Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo (USP), Bauru, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0003-3051-737X
Juliane Maria Guerreiro-TanomaruDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0446-2037
Mário Tanomaru-FilhoDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil. tanomaru@uol.com.br.ORCID http://orcid.org/0000-0002-2574-4706

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/11011-7Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/11012-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/13106-3Fundação de Amparo à Pesquisa do Estado de São Paulo,Brazil 2021/11496-3
6 · The paper itself

Abstract

objectiveTo evaluate the performance in endodontic retreatment and pericervical dentin preservation using ProDesign Logic (PDL), Reciproc Blue (RB), and WaveOne Gold (WOG) NiTi systems in first (MB1) and second (MB2) mesiobuccal root canals of maxillary molars, using cone-beam computed tomography (CBCT) and micro-computed tomography (micro-CT). MATERIALS AND

methodsMB1 and MB2 canals were prepared, filled, and randomized into four groups (n = 8). MB1 were retreated using PDL up to file 40/0.05 or RB R40 (40/0.06), while MB2 were retreated using PDL up to file 35/0.05 or WOG (35/0.06). Micro-CT scans were performed before and after retreatment to assess the remaining filling material, canal transportation, and canal centralization. Dentin removal and remaining dentin were measured at four levels below the furcation through CBCT scans analyzed with the e-Vol DX software, with micro-CT serving as the reference standard.

resultsRB was more effective than PDL in removing MB1 filling material, while PDL outperformed WOG in the apical third of MB2 (p < 0.05). Overall, CBCT measurements for dentin removal were consistent with micro-CT in MB1 but occasionally underestimated in MB2 (p < 0.05). A significant reduction in MB2 danger zone dentin thickness below 0.5 mm was observed after retreatment (p < 0.05).

conclusionsRB was more effective in retreating MB1, while PDL was more efficient in the apical third of MB2. A substantial decrease in dentin thickness in the MB2 danger zone was noted after retreatment, regardless of the NiTi system or imaging modality used. Overall, CBCT scans provided consistent assessments of dentin. CLINICAL RELEVANCE: Selecting appropriate NiTi systems minimizes dentin removal in MB1 and MB2 danger zones, reducing the risk of perforation in the furcation area. CBCT reliably assesses dentin thickness, aiding clinical decisions and improving endodontic retreatment outcomes.

Indexed as

Cone-Beam Computed TomographyDental AlloysDental Pulp CavityNickelRoot Canal PreparationRoot Canal TherapyTitaniumX-Ray MicrotomographyHumansIn Vitro TechniquesMolarRetreatmentDental AlloysNickelTitaniumtitanium nickelideCone-beam computed tomographicDentine thicknessEndodontic retreatmentMaxillary molarsMicro-computed tomography

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.