Evidence map›Paper›PMID 40105920›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Association of stroke and mortality among patients receiving heart transplantation-a nationwide study.

Wei-Syun Hu, Cheng-Li Lin

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Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Wei-Syun HuSchool of Medicine, College of Medicine, China Medical University, Taichung, 40402, Taiwan. weisyunhu@gmail.com.
Cheng-Li LinManagement Office for Health Data, China Medical University Hospital, Taichung, 40447, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to define the association of heart transplantation with incident stroke, cardiovascular (CV) and all-cause death. The incidence rate (IR) was calculated by dividing the number of outcomes by the summed person-years in the group during the follow-up period. Crude and adjusted hazard ratios (HRs) and the corresponding 95% confidence intervals (CIs) were estimated through univariable and multivariable Cox proportional hazards models. Propensity score (PS) matching analysis was adopted to minimize the differences between the two cohorts. Each cohort had 13,948 study participants. Compared to the control group, patients with heart transplantation had a higher risk of stroke (adjusted HR [95% CI] = 2.96 [2.72, 3.22]) and CV death (adjusted HR [95% CI] = 5.33 [4.87, 5.83]), and the risk is higher in the subgroup of the male sex, without comorbidity, and follow-up period < 10 years.  Among patients who underwent cardiac transplantation, the subgroups of the male sex, without comorbidities and short follow-up period are at higher risk for incident stroke and CV death.

Indexed as

Cardiovascular DiseasesHeart TransplantationStrokeAdultAgedCause of DeathFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRisk FactorsTaiwanDeathHeart transplantationStroke

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.