Evidence map›Paper›PMID 40105908›Full record

ArticleInternational endodontic journal2025

Association between apical periodontitis and psoriasis vulgaris: A cross-sectional study.

Crystal Marruganti, Giulia Malvicini, Elisa Cinotti, Aurora Fuso, Emanuele Trovato, Pietro Rubegni, Simone Grandini, Carlo Gaeta

Abstract read
In one paragraph

Article in International endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Crystal MarrugantiUnit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0003-1088-2046
Giulia MalviciniUnit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0001-5968-6471
Elisa CinottiUnit of Dermatology, Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.ORCID 0000-0002-4009-0659
Aurora FusoUnit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Emanuele TrovatoUnit of Dermatology, Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.ORCID 0000-0001-8301-9206
Pietro RubegniUnit of Dermatology, Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy.ORCID 0000-0002-7762-9312
Simone GrandiniUnit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0002-6723-2784
Carlo GaetaUnit of Endodontics and Restorative Dentistry, Department of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0002-2736-8046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the prevalence of apical periodontitis (AP) and caries in subjects with psoriasis vulgaris. METHODOLOGY: In total, 152 patients with psoriasis vulgaris were included in the study. The severity and extent of psoriasis were assessed according to the Psoriasis Area Severity Index (PASI), the Body Surface Area (BSA) and the Physician's Global Assessment Scale (PGA). Periapical status was assessed through dental examination and periapical radiographs. Data regarding the Periapical Index (PAI), caries experience expressed as the Decayed, Missing, Filled Teeth Index (DMFT) and psoriasis medications were recorded. A predictive logistic regression model for the presence of AP and a linear regression model were then built to relate the severity and extent of AP to the type of drug therapy taken for psoriasis and to the severity and extent of the skin disease.

resultsSubjects with severe/moderate psoriasis showed a significantly higher prevalence of AP (p = .002) and a higher PAI score (p = .0035) than subjects with mild psoriasis. No significant correlation was found between AP and caries experience (p = .76). The logistic regression model showed that moderate/severe psoriasis increased the odds of having AP [odds ratio (OR) = 1.30 ± 1.088, 1.55]. A negative linear relationship between biological drug intake and PAI score value was observed (coefficient = -.54; p = .04).

conclusionsThe degree of severity of psoriasis is significantly associated with AP, suggesting that psoriasis may play a role in the pathogenesis of AP. However, no significant correlation was observed for caries experience. Furthermore, the immune-modulating drugs taken by these patients did not seem to have different effects on the prevalence of AP.

Indexed as

Periapical PeriodontitisPsoriasisAdultCross-Sectional StudiesDental CariesFemaleHumansMaleMiddle AgedPrevalenceSeverity of Illness Indexdental cariesperiapical periodontitispsoriasis

Identifiers

PMID40105908
PMCPMC12065119

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.